Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | NR3C1 | P04150 | 6/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.35 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 4/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9750099 | 0.79 | CYP2C19 (0.47) | TSHRNR1H2NR1H3CYP2C19CNR2 | |
| SCHEMBL9749583 | 0.79 | TSHR (0.50) | TSHRNR3C1NR1H2NR1H3CYP2C19 | |
| SCHEMBL1533790 | 0.78 | TSHR (0.48) | TSHRATMNR3C1CYP2C19CNR2 | |
| SCHEMBL11160283 | 0.77 | NR3C1 (0.43) | TSHRNR3C1CYP2C19PGRNR3C2 | |
| SCHEMBL3426887 | 0.72 | TSHR (0.52) | TSHRALDH1A1KDM4E | |
| SCHEMBL8086502 | 0.71 | ALDH1A1 (0.49) | CNR2ALDH1A1KDM4E | |
| SCHEMBL11306094 | 0.69 | TSHR (0.54) | TSHRNR3C1NR1H2NR1H3CYP2C19 | |
| SCHEMBL5406966 | 0.68 | NR3C1 (0.42) | TSHRNR3C1CYP2C19PGRNR3C2 | |
| SCHEMBL7148219 | 0.68 | TSHR (0.54) | TSHRNR3C1CYP2C19CNR2PGR | |
| SCHEMBL11348653 | 0.68 | TSHR (0.41) | TSHRATMNR3C1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5118986-A | Electroluminescent device | RICOH COMPANY, LTD. (JP) | 1992-06-02 | — | — | US | claimed |