Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.38 |
| ▸ | CRHR1 | P34998 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.37 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.37 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.37 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11308287 | 0.75 | TSHR (0.38) | TSHRCYP2D6NPSR1SLC6A2SLC6A3 | |
| SCHEMBL9749583 | 0.74 | TSHR (0.50) | TSHRAOC3CYP2C19NR3C1 | |
| SCHEMBL11306094 | 0.74 | TSHR (0.54) | TSHRAOC3CYP2C19NR3C1 | |
| SCHEMBL1533790 | 0.74 | TSHR (0.48) | TSHRCYP2D6NPSR1SLC6A2SLC6A4 | |
| SCHEMBL11160283 | 0.72 | NR3C1 (0.43) | TSHRCYP2D6NPSR1L3MBTL1SLC6A2 | |
| SCHEMBL11315361 | 0.71 | TSHR (0.47) | TSHRL3MBTL1CYP2C19NR3C1ATM | |
| SCHEMBL659227 | 0.71 | CRHR1 (0.36) | TSHRCYP2D6SIGMAR1CRHR1NPSR1 | |
| SCHEMBL641218 | 0.71 | TSHR (0.70) | TSHRCYP2D6TAAR1SLC6A3AOC3 | |
| SCHEMBL23193646 | 0.70 | GABRA1 (0.36) | TSHRCYP2D6SIGMAR1CRHR1NPSR1 | |
| SCHEMBL5406966 | 0.70 | NR3C1 (0.42) | TSHRNPSR1L3MBTL1SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4268439-A | Basic azo dyestuffs having benzylammoniumamine substituent in the coupling component | BAYER AKTIENGESELLSCHAFT (DE) | 1981-05-19 | — | — | US | disclosed |