Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | LTA4H | P09960 | 2/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9750256 | 0.85 | ALDH1A1 (0.35) | ALDH1A1HTTLMNAMAPK1L3MBTL1 | |
| SCHEMBL9750451 | 0.81 | ALDH1A1 (0.44) | ALDH1A1HTTLMNAL3MBTL1GAA | |
| SCHEMBL9750191 | 0.75 | PDK2 (0.39) | ALDH1A1LMNAL3MBTL1HPGDGAA | |
| SCHEMBL10646796 | 0.72 | ALDH1A1 (0.34) | ALDH1A1LMNAMAPK1CYP1A2MEN1 | |
| SCHEMBL9750257 | 0.71 | GRIA2 (0.42) | ALDH1A1POLBLTA4HMEN1KMT2A | |
| SCHEMBL9750259 | 0.71 | MAPT (0.46) | ALDH1A1MAPK1L3MBTL1HPGDGAA | |
| SCHEMBL4603103 | 0.71 | MEN1 (0.37) | ALDH1A1HTTLMNAGAAPOLB | |
| SCHEMBL9750080 | 0.69 | ALDH1A1 (0.39) | ALDH1A1HTTLMNAMAPK1L3MBTL1 | |
| SCHEMBL9750447 | 0.69 | PGR (0.33) | ALDH1A1LMNAMAPK1L3MBTL1PGR | |
| SCHEMBL11020994 | 0.69 | MAPT (0.45) | ALDH1A1HTTLMNAL3MBTL1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5120858-A | Condensation of 2-methyleneindoline and formic acid in acetic anhydride | MILES INC. (US) | 1992-06-09 | — | — | US | disclosed |
| EP-0058863-B1 | PROCESS FOR THE PREPARATION OF TRIMETHINE DYESTUFFS | BAYER AG (DE) | 1985-01-23 | — | — | EP | disclosed |
| US-4419511-A | Process for the preparation of trimethine dyestuffs | BAYER AKTIENGESELLSCHAFT (US) | 1983-12-06 | — | — | US | disclosed |
| EP-0058863-A1 | Process for the preparation of trimethine dyestuffs | BAYER AG (DE) | 1982-09-01 | — | — | EP | disclosed |