Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | RECQL | P46063 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | DAO | P14920 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.31 |
| ▸ | GRK6 | P43250 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9750259 | 0.83 | MAPT (0.46) | L3MBTL1MAPTMEN1KMT2AGAA | |
| SCHEMBL9750256 | 0.83 | ALDH1A1 (0.35) | PDK2L3MBTL1MAPTKDM4EMEN1 | |
| SCHEMBL9750080 | 0.81 | ALDH1A1 (0.39) | L3MBTL1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL11020994 | 0.80 | MAPT (0.45) | L3MBTL1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL11019576 | 0.79 | MAPT (0.46) | L3MBTL1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL9750187 | 0.76 | PDK2 (0.42) | PDK2MAPTKDM4EMEN1KMT2A | |
| SCHEMBL9750033 | 0.75 | ALDH1A1 (0.38) | L3MBTL1MEN1KMT2AGAALMNA | |
| SCHEMBL4603103 | 0.74 | MEN1 (0.37) | MAPTKDM4EMEN1KMT2ARECQL | |
| SCHEMBL10938890 | 0.73 | GABRA1 (0.34) | LMNAALDH1A1TDP1HPGD | |
| SCHEMBL9750447 | 0.72 | PGR (0.33) | L3MBTL1MAPTRECQLLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5120858-A | Condensation of 2-methyleneindoline and formic acid in acetic anhydride | MILES INC. (US) | 1992-06-09 | — | — | US | disclosed |
| US-4419511-A | Process for the preparation of trimethine dyestuffs | BAYER AKTIENGESELLSCHAFT (US) | 1983-12-06 | — | — | US | disclosed |
| US-4349670-A | Process for the preparation of cationic dyestuffs | BAYER AKTIENGESELLSCHAFT (DE) | 1982-09-14 | — | — | US | disclosed |
| EP-0058863-A1 | Process for the preparation of trimethine dyestuffs | BAYER AG (DE) | 1982-09-01 | — | — | EP | disclosed |
| EP-0023652-A1 | Process for the preparation of cationic dyestuffs | BAYER AG (DE) | 1981-02-11 | — | — | EP | disclosed |
| US-4201707-A | Methine dyestuffs containing a phenyl azo group | BAYER AKTIENGESELLSCHAFT (DE) | 1980-05-06 | — | — | US | disclosed |
| US-4143228-A | RED SHADES | BAYER AKTIENGESELLSCHAFT (DE) | 1979-03-06 | — | — | US | disclosed |
| US-4138570-A | METHINE DYE | BAYER AKTIENGESELLSCHAFT (DE) | 1979-02-06 | — | — | US | disclosed |