Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | LIPE | Q05469 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 3/20 | 0.39 |
| ▸ | ALPG | P10696 | 1/20 | 0.38 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 5/20 | 0.38 |
| ▸ | DRD2 | P14416 | 2/20 | 0.38 |
| ▸ | HTR6 | P50406 | 1/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9750080 | 0.90 | ALDH1A1 (0.39) | MAPTMAPK1TDP1L3MBTL1ALDH1A1 | |
| SCHEMBL11020994 | 0.88 | MAPT (0.45) | MAPTTDP1L3MBTL1ALDH1A1HPGD | |
| SCHEMBL11019682 | 0.83 | MAPT (0.40) | MAPTMAPK1TDP1L3MBTL1ALDH1A1 | |
| SCHEMBL9750191 | 0.83 | PDK2 (0.39) | MAPTTDP1L3MBTL1ALDH1A1HPGD | |
| SCHEMBL11019576 | 0.82 | MAPT (0.46) | MAPTTDP1L3MBTL1ALDH1A1HPGD | |
| SCHEMBL11149823 | 0.80 | MAPT (0.47) | MAPTMAPK1TDP1L3MBTL1ALDH1A1 | |
| SCHEMBL9750127 | 0.79 | BRD4 (0.34) | MAPTMAPK1TDP1L3MBTL1ALDH1A1 | |
| SCHEMBL9750256 | 0.78 | ALDH1A1 (0.35) | MAPTMAPK1L3MBTL1ALDH1A1HPGD | |
| SCHEMBL11019010 | 0.76 | HTR2A (0.33) | L3MBTL1DRD2HTR6 | |
| SCHEMBL9750449 | 0.75 | MAPT (0.40) | MAPTMAPK1TDP1L3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5120858-A | Condensation of 2-methyleneindoline and formic acid in acetic anhydride | MILES INC. (US) | 1992-06-09 | — | — | US | disclosed |
| EP-0058863-B1 | PROCESS FOR THE PREPARATION OF TRIMETHINE DYESTUFFS | BAYER AG (DE) | 1985-01-23 | — | — | EP | disclosed |
| US-4419511-A | Process for the preparation of trimethine dyestuffs | BAYER AKTIENGESELLSCHAFT (US) | 1983-12-06 | — | — | US | disclosed |