Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | AR | P10275 | 2/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9750033 | 0.81 | ALDH1A1 (0.38) | ALDH1A1GAAL3MBTL1LMNAHTT | |
| SCHEMBL9750256 | 0.77 | ALDH1A1 (0.35) | ALDH1A1GAAL3MBTL1SMN1; SMN2LMNA | |
| SCHEMBL9750191 | 0.73 | PDK2 (0.39) | ALDH1A1GAAL3MBTL1LMNANPSR1 | |
| SCHEMBL9750080 | 0.73 | ALDH1A1 (0.39) | ALDH1A1L3MBTL1SMN1; SMN2LMNAHTT | |
| SCHEMBL4603103 | 0.72 | MEN1 (0.37) | ALDH1A1GAALMNAHTTTDP1 | |
| SCHEMBL9750259 | 0.69 | MAPT (0.46) | ALDH1A1GAAL3MBTL1TDP1KMT2A | |
| SCHEMBL5541683 | 0.69 | ALDH1A1 (0.64) | ALDH1A1GAAL3MBTL1ARACHE | |
| SCHEMBL9750447 | 0.67 | PGR (0.33) | ALDH1A1L3MBTL1SMN1; SMN2LMNATDP1 | |
| SCHEMBL11020994 | 0.67 | MAPT (0.45) | ALDH1A1GAAL3MBTL1SMN1; SMN2LMNA | |
| SCHEMBL11019576 | 0.66 | MAPT (0.46) | ALDH1A1GAAL3MBTL1SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5120858-A | Condensation of 2-methyleneindoline and formic acid in acetic anhydride | MILES INC. (US) | 1992-06-09 | — | — | US | disclosed |
| EP-0058863-B1 | PROCESS FOR THE PREPARATION OF TRIMETHINE DYESTUFFS | BAYER AG (DE) | 1985-01-23 | — | — | EP | disclosed |
| US-4419511-A | Process for the preparation of trimethine dyestuffs | BAYER AKTIENGESELLSCHAFT (US) | 1983-12-06 | — | — | US | disclosed |
| EP-0058863-A1 | Process for the preparation of trimethine dyestuffs | BAYER AG (DE) | 1982-09-01 | — | — | EP | disclosed |