Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 3/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.40 |
| ▸ | YAP1 | P46937 | 1/20 | 0.40 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.40 |
| ▸ | TEAD2 | Q15562 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CDK1 | P06493 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9808195 | 0.87 | HTT (0.52) | TDP1HSP90AA1RXFP1CA2CA1 | |
| SCHEMBL9808079 | 0.87 | HPGD (0.51) | TDP1HSP90AA1RXFP1CA2CA1 | |
| SCHEMBL9808172 | 0.82 | TDP1 (0.45) | TDP1HSP90AA1RXFP1CNR2MEN1 | |
| SCHEMBL9750096 | 0.81 | THRB (0.45) | TDP1CA2CA1MEN1RAB9A | |
| SCHEMBL9808307 | 0.78 | HTT (0.53) | TDP1CA2CA1TEAD1YAP1 | |
| SCHEMBL8387623 | 0.78 | TRPV1 (0.53) | TDP1HSP90AA1RXFP1CNR2MEN1 | |
| SCHEMBL9808178 | 0.78 | HSP90AA1 (0.45) | TDP1HSP90AA1RXFP1CA2TEAD1 | |
| SCHEMBL9554829 | 0.75 | CA2 (0.50) | TDP1CA2CA1THRBKDM4E | |
| SCHEMBL9808197 | 0.75 | MAPT (0.38) | TDP1HSP90AA1CA2CA1TEAD1 | |
| SCHEMBL9808068 | 0.74 | TDP1 (0.38) | TDP1CA2MEN1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4985393-A | Bis/hydroxyphenylthio/ Compounds | KANZAKI PAPER MANUFACTURING CO., LTD. (JP) | 1991-01-15 | — | — | US | disclosed |
| EP-0373561-A2 | Heat sensitive recording material | KANZAKI PAPER MANUFACTURING CO., LTD. (JP) | 1990-06-20 | — | — | EP | disclosed |