Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.43 |
| ▸ | YAP1 | P46937 | 1/20 | 0.43 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.43 |
| ▸ | TEAD2 | Q15562 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9808195 | 0.89 | HTT (0.52) | HPGDKDM4ETDP1CA2CA1 | |
| SCHEMBL9808044 | 0.87 | TDP1 (0.51) | KDM4ETDP1CA2CA1HTT | |
| SCHEMBL9808307 | 0.81 | HTT (0.53) | HPGDKDM4ETDP1CA2CA1 | |
| SCHEMBL9808237 | 0.81 | KDM4E (0.55) | HPGDKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL9808036 | 0.80 | HPGD (0.62) | HPGDKDM4ETEAD1YAP1TEAD4 | |
| SCHEMBL9750096 | 0.77 | THRB (0.45) | KDM4ETDP1CA2CA1MEN1 | |
| SCHEMBL9808286 | 0.76 | HTT (0.56) | HPGDKDM4ETDP1HTTTEAD1 | |
| SCHEMBL9808042 | 0.75 | HPGD (0.56) | HPGDKDM4ETDP1HTTTEAD1 | |
| SCHEMBL9808064 | 0.75 | HPGD (0.53) | HPGDKDM4ETEAD1YAP1TEAD4 | |
| SCHEMBL9808054 | 0.73 | HTT (0.49) | HPGDKDM4ETDP1HTTHSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4985393-A | Bis/hydroxyphenylthio/ Compounds | KANZAKI PAPER MANUFACTURING CO., LTD. (JP) | 1991-01-15 | — | — | US | disclosed |
| EP-0373561-A2 | Heat sensitive recording material | KANZAKI PAPER MANUFACTURING CO., LTD. (JP) | 1990-06-20 | — | — | EP | disclosed |