Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 6/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 7/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | TYR | P14679 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | ELANE | P08246 | 2/20 | 0.39 |
| ▸ | CTSG | P08311 | 2/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5382807 | 0.81 | CA2 (0.43) | ALOX5MEN1HTTKMT2ATYR | |
| SCHEMBL8610020 | 0.81 | POLB (0.53) | ALOX5MEN1HTTKMT2ATYR | |
| SCHEMBL2363780 | 0.81 | POLB (0.53) | ALOX5MEN1HTTKMT2ATYR | |
| SCHEMBL5374401 | 0.80 | CA2 (0.42) | ALOX5MEN1HTTKMT2ATYR | |
| SCHEMBL258494 | 0.80 | GABRA1 (0.46) | CYP3A4MAPTALOX15TSHRCA2 | |
| SCHEMBL8971610 | 0.78 | ALOX5 (0.70) | ALOX5PTGS2MEN1HTTKMT2A | |
| SCHEMBL8588879 | 0.76 | PTGS2 (0.71) | ALOX5PTGS2MEN1HTTKMT2A | |
| SCHEMBL127023 | 0.76 | PTGS2 (0.71) | ALOX5PTGS2MEN1HTTKMT2A | |
| SCHEMBL1160403 | 0.76 | PTGS2 (0.63) | ALOX5PTGS2HTTCYP3A4TP53 | |
| SCHEMBL8367626 | 0.76 | PTGS2 (0.71) | ALOX5PTGS2MEN1HTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5084593-A | Cyanine, aniline dyes for heat sensitive recording elements | RICOH COMPANY, LTD. (JP) | 1992-01-28 | — | — | US | disclosed |
| US-5008238-A | Thermosensitive material with phenolic developer | RICOH COMPANY, LTD. (JP) | 1991-04-16 | — | — | US | disclosed |