Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ATP4A | P20648 | 1/20 | 0.37 |
| ▸ | ATP4B | P51164 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 2/20 | 0.37 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.37 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.37 |
| ▸ | PTGER4 | P35408 | 4/20 | 0.37 |
| ▸ | PTGER3 | P43115 | 4/20 | 0.37 |
| ▸ | PTGER2 | P43116 | 4/20 | 0.37 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9750193 | 0.82 | MAPT (0.41) | L3MBTL1MAPTMAPK1TDP1HTR1A | |
| SCHEMBL11149823 | 0.80 | MAPT (0.47) | L3MBTL1MAPTMAPK1TDP1HTR1A | |
| SCHEMBL11018961 | 0.74 | POLB (0.42) | PTPN1L3MBTL1MAPTMAPK1TDP1 | |
| SCHEMBL9750449 | 0.73 | MAPT (0.40) | L3MBTL1MAPTMAPK1TDP1ATP4A | |
| SCHEMBL9750432 | 0.73 | HRH3 (0.48) | MEN1KMT2ANPC1RAB9AMAOB | |
| SCHEMBL6859897 | 0.71 | MPI (0.32) | TDP1 | |
| SCHEMBL11019035 | 0.70 | HRH3 (0.48) | MEN1KMT2ALMNANPC1RAB9A | |
| SCHEMBL18716386 | 0.70 | HTR1A (0.61) | PTPN1L3MBTL1MAPTMAPK1TDP1 | |
| SCHEMBL10939899 | 0.70 | ALDH1A1 (0.52) | L3MBTL1MAPTMAPK1TDP1ALDH1A1 | |
| SCHEMBL11444474 | 0.70 | NR1H2 (0.36) | L3MBTL1ALDH1A1MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5120858-A | Condensation of 2-methyleneindoline and formic acid in acetic anhydride | MILES INC. (US) | 1992-06-09 | — | — | US | disclosed |
| EP-0058863-B1 | PROCESS FOR THE PREPARATION OF TRIMETHINE DYESTUFFS | BAYER AG (DE) | 1985-01-23 | — | — | EP | disclosed |
| US-4419511-A | Process for the preparation of trimethine dyestuffs | BAYER AKTIENGESELLSCHAFT (US) | 1983-12-06 | — | — | US | disclosed |
| EP-0058863-A1 | Process for the preparation of trimethine dyestuffs | BAYER AG (DE) | 1982-09-01 | — | — | EP | disclosed |