Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 4/20 | 0.38 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.38 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.38 |
| ▸ | PDE4A | P27815 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.36 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11149823 | 0.83 | MAPT (0.47) | MAPTALDH1A1MAPK1TDP1L3MBTL1 | |
| SCHEMBL9750186 | 0.82 | PTPN1 (0.40) | MAPTALDH1A1MAPK1TDP1L3MBTL1 | |
| SCHEMBL9750009 | 0.76 | CHRNA7 (0.46) | MAPTALDH1A1HSD17B10KDM4CMAPK1 | |
| SCHEMBL9750259 | 0.72 | MAPT (0.46) | MAPTALDH1A1MAPK1TDP1L3MBTL1 | |
| SCHEMBL17912878 | 0.72 | MAPT (0.66) | MAPTMAPK1TDP1L3MBTL1HTR1A | |
| SCHEMBL9750449 | 0.72 | MAPT (0.40) | MAPTALDH1A1MAPK1TDP1L3MBTL1 | |
| SCHEMBL9750432 | 0.71 | HRH3 (0.48) | KDM4CMAOBNPC1RAB9A | |
| SCHEMBL6312645 | 0.69 | HTR1A (0.63) | MAPTMAPK1TDP1L3MBTL1HTR1A | |
| SCHEMBL11019035 | 0.68 | HRH3 (0.48) | KDM4CMAOBNPC1RAB9A | |
| SCHEMBL5850231 | 0.67 | HTR7 (0.41) | MAPTALDH1A1MAPK1ADRA1ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5120858-A | Condensation of 2-methyleneindoline and formic acid in acetic anhydride | MILES INC. (US) | 1992-06-09 | — | — | US | disclosed |
| EP-0058863-B1 | PROCESS FOR THE PREPARATION OF TRIMETHINE DYESTUFFS | BAYER AG (DE) | 1985-01-23 | — | — | EP | disclosed |
| US-4419511-A | Process for the preparation of trimethine dyestuffs | BAYER AKTIENGESELLSCHAFT (US) | 1983-12-06 | — | — | US | disclosed |