Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APEX1 | P27695 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.40 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.40 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.40 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.40 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.40 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.40 |
| ▸ | PRNP | P04156 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12964413 | 0.83 | PLA2G4A (0.48) | ALDH1A1L3MBTL1PLA2G4APTGER3PTGER2 | |
| SCHEMBL9749568 | 0.82 | L3MBTL1 (0.43) | ALDH1A1GAAPOLBHPGDSMN1; SMN2 | |
| SCHEMBL9749078 | 0.80 | APEX1 (0.50) | APEX1ALDH1A1HSD17B10GAAPOLB | |
| SCHEMBL12964364 | 0.79 | PLA2G4A (0.46) | ALDH1A1L3MBTL1PLA2G4AKDM4ETDP1 | |
| SCHEMBL7024852 | 0.76 | PTGER3 (0.41) | PTGER3PTGER2PTGER4 | |
| SCHEMBL6825656 | 0.75 | L3MBTL1 (0.48) | ALDH1A1TSHRL3MBTL1PLA2G4AKDM4E | |
| SCHEMBL1811039 | 0.72 | GAA (0.55) | ALDH1A1HSD17B10GAAPOLBHPGD | |
| SCHEMBL10969470 | 0.72 | SMN1; SMN2 (0.54) | ALDH1A1HSD17B10GAAPOLBHPGD | |
| SCHEMBL9749240 | 0.72 | L3MBTL1 (0.41) | ALDH1A1SMN1; SMN2L3MBTL1PLA2G4APTGER3 | |
| SCHEMBL9481442 | 0.72 | L3MBTL1 (0.46) | ALDH1A1TSHRL3MBTL1PLA2G4AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0194572-B1 | HETEROCYCLIC SULFIDES, PROCESS FOR THEIR PREPARATION AND MEDICAMENTS CONTAINING THEM | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-01-02 | — | — | EP | disclosed |
| US-4762848-A | IMMUNE SYSTEM STIMULANTS, CYTOSTATIC AGENTS | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-08-09 | — | — | US | disclosed |
| EP-0194572-A1 | Heterocyclic sulfides, process for their preparation and Medicaments containing them | HOECHST AKTIENGESELLSCHAFT (DE) | 1986-09-17 | — | — | EP | disclosed |