Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER3 | P43115 | 13/20 | 0.41 |
| ▸ | PTGER2 | P43116 | 13/20 | 0.41 |
| ▸ | PTGER4 | P35408 | 10/20 | 0.41 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7022732 | 0.88 | HTR2B (0.36) | PTGER3PTGER2PTGER4PTGER1 | |
| SCHEMBL7019281 | 0.81 | RAB9A (0.49) | — | |
| SCHEMBL7025782 | 0.77 | HTR1A (0.41) | — | |
| SCHEMBL9750229 | 0.76 | APEX1 (0.53) | PTGER3PTGER2PTGER4 | |
| SCHEMBL12964413 | 0.76 | PLA2G4A (0.48) | PTGER3PTGER2PTGER4PTGER1 | |
| SCHEMBL7023733 | 0.75 | RAB9A (0.31) | — | |
| SCHEMBL9749568 | 0.73 | L3MBTL1 (0.43) | — | |
| SCHEMBL12964364 | 0.73 | PLA2G4A (0.46) | PTGER3PTGER2PTGER4 | |
| SCHEMBL8752079 | 0.71 | ALOX15 (0.38) | — | |
| SCHEMBL7025903 | 0.71 | APEX1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0749433-B1 | (4,4-DIFLUOROBUT-3-ENYLTHIO)-SUBSTITUTED HETEROCYCLIC OR CARBOCYCLIC RING COMPOUNDS HAVING PESTICIDAL ACTIVITY | SYNGENTA LTD (GB) | 2003-05-07 | — | — | EP | disclosed |
| US-5952359-A | NEMATICIDES, INSECTICIDES AND MITICIDES; 1,1-DIFLUORO-3-(THIAZOLYL OR ISOTHIAZOYL-THIO (OR SULFINYL OR SULFONYL)-PROP-1-ENE DERIVATIVES | ZENECA LIMITED (GB) | 1999-09-14 | — | — | US | disclosed |
| US-5912243-A | NOVEL COMPOUNDS FOR CONTROLLING NEMATODES, INSECT OR ACARID PESTS | ZENECA LIMITED (GB) | 1999-06-15 | — | — | US | disclosed |
| US-5705516-A | NEMATOCIDES, INSECTICIDES, ACARICIDES | ZENECA LIMITED (GB) | 1998-01-06 | — | — | US | disclosed |
| CN-1143958-A | (4,4-difluorobut-3-enylthio-)-substituted heterocyclic or carbocyclic ring compounds | ZENECA LTD (GB) | 1997-02-26 | — | — | CN | disclosed |