Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APEX1 | P27695 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | PRNP | P04156 | 2/20 | 0.38 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.37 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9749270 | 0.87 | L3MBTL1 (0.39) | ALDH1A1HSD17B10GAAPOLBSMN1; SMN2 | |
| SCHEMBL9750229 | 0.80 | APEX1 (0.53) | APEX1ALDH1A1HSD17B10GAAPOLB | |
| SCHEMBL2655261 | 0.73 | GABRA5 (0.68) | ALDH1A1HSD17B10TSHRSMN1; SMN2KDM4E | |
| SCHEMBL8044281 | 0.73 | GABRA5 (0.41) | HSD17B10GABRA5GABRB2HDAC1HDAC6 | |
| SCHEMBL8538449 | 0.73 | MAPT (0.54) | ALDH1A1GAAPOLBSMN1; SMN2TDP1 | |
| SCHEMBL1812618 | 0.70 | POLB (0.63) | ALDH1A1GAAPOLBTSHRSMN1; SMN2 | |
| SCHEMBL8538010 | 0.70 | HDAC6 (0.47) | HSD17B10GABRA5GABRB2HDAC1HDAC6 | |
| SCHEMBL10969470 | 0.70 | SMN1; SMN2 (0.54) | ALDH1A1HSD17B10GAAPOLBTSHR | |
| SCHEMBL5512924 | 0.69 | SLC6A3 (0.47) | ALDH1A1HSD17B10GAANPC1RAB9A | |
| SCHEMBL9096766 | 0.68 | CA2 (0.42) | HSD17B10GABRA5GABRB2HDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0194572-B1 | HETEROCYCLIC SULFIDES, PROCESS FOR THEIR PREPARATION AND MEDICAMENTS CONTAINING THEM | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-01-02 | — | — | EP | disclosed |
| US-4762848-A | IMMUNE SYSTEM STIMULANTS, CYTOSTATIC AGENTS | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-08-09 | — | — | US | disclosed |
| EP-0194572-A1 | Heterocyclic sulfides, process for their preparation and Medicaments containing them | HOECHST AKTIENGESELLSCHAFT (DE) | 1986-09-17 | — | — | EP | disclosed |