Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | SCN1A | P35498 | 1/20 | 0.32 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.32 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.32 |
| ▸ | LTA4H | P09960 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | TSPO | P30536 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9750033 | 0.89 | ALDH1A1 (0.38) | ALDH1A1SLC6A2SLC6A4HPGDLMNA | |
| SCHEMBL9750451 | 0.86 | ALDH1A1 (0.44) | ALDH1A1LMNAKMT2AGAAHTT | |
| SCHEMBL9750256 | 0.81 | ALDH1A1 (0.35) | ALDH1A1SLC6A2SLC6A4HPGDLMNA | |
| SCHEMBL9750259 | 0.79 | MAPT (0.46) | BRD4ALDH1A1HPGDKMT2AGAA | |
| SCHEMBL9750191 | 0.78 | PDK2 (0.39) | ALDH1A1HPGDLMNAKMT2AGAA | |
| SCHEMBL4603103 | 0.73 | MEN1 (0.37) | ALDH1A1LMNAKMT2AGAAHTT | |
| SCHEMBL11019576 | 0.72 | MAPT (0.46) | ALDH1A1HPGDLMNAKMT2AGAA | |
| SCHEMBL9750080 | 0.71 | ALDH1A1 (0.39) | ALDH1A1HPGDLMNAKMT2AMAPK1 | |
| SCHEMBL9750447 | 0.71 | PGR (0.33) | ALDH1A1LMNAMAPK1L3MBTL1MAPT | |
| SCHEMBL8942200 | 0.71 | GRIA2 (0.42) | LMNAMAPK1HTTLTA4HTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4172892-A | Heteromonocyclic and heterobicyclic derivatives of unsaturated 7-acylamido-3-cephem-4-carboxylic acid | CARLO ERBA S.P.A. (IT) | 1979-10-30 | — | — | US | claimed |
| US-5120858-A | Condensation of 2-methyleneindoline and formic acid in acetic anhydride | MILES INC. (US) | 1992-06-09 | — | — | US | disclosed |
| EP-0058863-B1 | PROCESS FOR THE PREPARATION OF TRIMETHINE DYESTUFFS | BAYER AG (DE) | 1985-01-23 | — | — | EP | disclosed |
| EP-0113920-A2 | Process for the manufacture of stable solutions of cationic methine dyes, and their use in spin dyeing | BAYER AG (DE) | 1984-07-25 | — | — | EP | disclosed |
| US-4419511-A | Process for the preparation of trimethine dyestuffs | BAYER AKTIENGESELLSCHAFT (US) | 1983-12-06 | — | — | US | disclosed |
| US-4388314-A | BACTERICIDES | FARMITALIA CARLO ERBA S.P.A. (IT) | 1983-06-14 | — | — | US | disclosed |
| EP-0058863-A1 | Process for the preparation of trimethine dyestuffs | BAYER AG (DE) | 1982-09-01 | — | — | EP | disclosed |
| US-4172892-A | Heteromonocyclic and heterobicyclic derivatives of unsaturated 7-acylamido-3-cephem-4-carboxylic acid | CARLO ERBA S.P.A. (IT) | 1979-10-30 | — | — | US | disclosed |