Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | STAT3 | P40763 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | LIPE | Q05469 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9750446 | 0.91 | ALDH1A1 (0.36) | MAPTL3MBTL1ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL9750259 | 0.83 | MAPT (0.46) | MAPTMAPK1TDP1L3MBTL1ALDH1A1 | |
| SCHEMBL9750254 | 0.80 | HRH3 (0.40) | TDP1L3MBTL1SMN1; SMN2GRM5HRH3 | |
| SCHEMBL9750449 | 0.80 | MAPT (0.40) | MAPTMAPK1TDP1L3MBTL1ALDH1A1 | |
| SCHEMBL9750080 | 0.79 | ALDH1A1 (0.39) | MAPTMAPK1TDP1L3MBTL1ALDH1A1 | |
| SCHEMBL9750009 | 0.77 | CHRNA7 (0.46) | MAPTMAPK1ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL9750432 | 0.74 | HRH3 (0.48) | HRH3MEN1KMT2ANPC1RAB9A | |
| SCHEMBL11020994 | 0.72 | MAPT (0.45) | MAPTTDP1L3MBTL1ALDH1A1HPGD | |
| SCHEMBL11019035 | 0.72 | HRH3 (0.48) | HRH3MEN1KMT2ANPC1RAB9A | |
| SCHEMBL11149823 | 0.71 | MAPT (0.47) | MAPTMAPK1TDP1L3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0058863-B1 | PROCESS FOR THE PREPARATION OF TRIMETHINE DYESTUFFS | BAYER AG (DE) | 1985-01-23 | — | — | EP | disclosed |
| US-4419511-A | Process for the preparation of trimethine dyestuffs | BAYER AKTIENGESELLSCHAFT (US) | 1983-12-06 | — | — | US | disclosed |