Luzindole

Luzindole

SCHEMBL9118261

CC(=O)NCCc1c(Cc2ccccc2)[nH]c2ccccc12.CC(=O)NCCc1c[nH]c2ccccc12

nearest known ligand 0.81

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 6/20 0.81
KMT2A Q03164 6/20 0.81
MTNR1A P48039 5/20 0.81
MTNR1B P49286 5/20 0.81
TSHR P16473 4/20 0.81
CYP1A2 P05177 3/20 0.81
CYP2C19 P33261 3/20 0.81
CYP3A4 P08684 3/20 0.81
TDP1 Q9NUW8 3/20 0.81
HPGD P15428 2/20 0.81
CYP2C9 P11712 1/20 0.81
LMNA P02545 1/20 0.69
PKM P14618 1/20 0.69
BLM P54132 1/20 0.69
MAPT P10636 3/20 0.60
ALDH1A1 P00352 2/20 0.60
ALOX15 P16050 2/20 0.60
CYP2D6 P10635 1/20 0.60
KDM4E B2RXH2 1/20 0.55
MAPK1 P28482 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Luzindole SCHEMBL4869000 0.90 MTNR1A (1.00) MEN1KMT2AMTNR1AMTNR1BTSHR
Nb-Acetyltryptamine SCHEMBL468850 0.83 MEN1 (1.00) MEN1KMT2AMTNR1AMTNR1BTSHR
SCHEMBL9401161 0.82 MTNR1A (0.84) MEN1KMT2AMTNR1AMTNR1BTSHR
Nb-Acetyltryptamine SCHEMBL29669230 0.82 MEN1 (0.97) MEN1KMT2AMTNR1AMTNR1BTSHR
SCHEMBL9751553 0.80 MTNR1A (0.79) MEN1KMT2AMTNR1AMTNR1BTSHR
SCHEMBL9401112 0.79 MTNR1A (0.79) MEN1KMT2AMTNR1AMTNR1BTSHR
SCHEMBL9302251 0.78 MTNR1A (0.77) MEN1KMT2AMTNR1AMTNR1BTSHR
SCHEMBL9303475 0.78 MTNR1A (0.72) MEN1KMT2AMTNR1AMTNR1BTSHR
SCHEMBL9304093 0.78 MTNR1A (0.75) MEN1KMT2AMTNR1AMTNR1BTSHR
SCHEMBL9303906 0.77 MTNR1A (0.71) MEN1KMT2AMTNR1AMTNR1BTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1995018629-A1 METHOD FOR TREATMENT AND PREVENTION OF DISEASE IN ANIMALS BIOMEDTECH ENGINEERING, INC. (US) 1995-07-13 WO disclosed