Pipecolic Acid — predicted protein targets

Predicted protein targets (top 12)

	gene	UniProt	supporting neighbours	confidence
▸	HSD17B10	Q99714	2/20	0.51

▸	SMN1; SMN2	Q16637	2/20	0.46

▸	RAB9A	P51151	1/20	0.41

▸	NPC1	O15118	1/20	0.41

▸	LMNA	P02545	2/20	0.39

▸	NPSR1	Q6W5P4	1/20	0.39

▸	CYP2C19	P33261	1/20	0.39

▸	ALDH1A1	P00352	1/20	0.39

▸	UCHL1	P09936	3/20	0.38

▸	USP30	Q70CQ3	2/20	0.37

▸	EPHX2	P34913	1/20	0.37

▸	HSD11B1	P28845	1/20	0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
Proline SCHEMBL6590813	0.94	HSD17B10 (0.55)	HSD17B10SMN1; SMN2RAB9ANPC1LMNA
SCHEMBL65490	0.87	HSD17B10 (0.63)	HSD17B10SMN1; SMN2RAB9ANPC1LMNA
SCHEMBL65491	0.87	HSD17B10 (0.63)	HSD17B10SMN1; SMN2RAB9ANPC1LMNA
SCHEMBL77858	0.87	HSD17B10 (0.63)	HSD17B10SMN1; SMN2RAB9ANPC1LMNA
SCHEMBL222955	0.85	HSD17B10 (0.62)	HSD17B10SMN1; SMN2RAB9ANPC1LMNA
SCHEMBL5898691	0.85	HSD17B10 (0.62)	HSD17B10SMN1; SMN2RAB9ANPC1LMNA
SCHEMBL18358031	0.85	HSD17B10 (0.62)	HSD17B10SMN1; SMN2RAB9ANPC1LMNA
SCHEMBL6219872	0.82	HSD17B10 (0.69)	HSD17B10SMN1; SMN2RAB9ANPC1LMNA
SCHEMBL85536	0.82	HSD17B10 (0.69)	HSD17B10SMN1; SMN2RAB9ANPC1LMNA
SCHEMBL67045	0.82	HSD17B10 (0.69)	HSD17B10SMN1; SMN2RAB9ANPC1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-1991000724-A1	ALKYNYL AMINES THAT REGULATE CHOLINERGIC NEUROTRANSMISSION	ABBOTT LABORATORIES (US)	1991-01-24	—	—	WO	disclosed