SCHEMBL5898691

SCHEMBL5898691

CC(C)(C)OC(=O)N1CCCCC[C@H]1C(=O)O

nearest known ligand 0.62

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ HSD17B10 Q99714 2/20 0.62
▸ SMN1; SMN2 Q16637 2/20 0.54
▸ RAB9A P51151 1/20 0.50
▸ NPC1 O15118 1/20 0.48
▸ LMNA P02545 2/20 0.48
▸ HPGD P15428 1/20 0.48
▸ CYP2C19 P33261 1/20 0.48
▸ ALDH1A1 P00352 2/20 0.47
▸ NPSR1 Q6W5P4 1/20 0.46
▸ EPHX1 P07099 1/20 0.46
▸ UCHL1 P09936 1/20 0.44
▸ MEN1 O00255 1/20 0.43
▸ KMT2A Q03164 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL222955 1.00 HSD17B10 (0.62) HSD17B10SMN1; SMN2RAB9ANPC1LMNA
SCHEMBL18358031 1.00 HSD17B10 (0.62) HSD17B10SMN1; SMN2RAB9ANPC1LMNA
SCHEMBL77858 0.98 HSD17B10 (0.63) HSD17B10SMN1; SMN2RAB9ANPC1LMNA
SCHEMBL65491 0.98 HSD17B10 (0.63) HSD17B10SMN1; SMN2RAB9ANPC1LMNA
SCHEMBL65490 0.98 HSD17B10 (0.63) HSD17B10SMN1; SMN2RAB9ANPC1LMNA
SCHEMBL6219872 0.93 HSD17B10 (0.69) HSD17B10SMN1; SMN2RAB9ANPC1LMNA
SCHEMBL67044 0.93 HSD17B10 (0.69) HSD17B10SMN1; SMN2RAB9ANPC1LMNA
SCHEMBL85536 0.93 HSD17B10 (0.69) HSD17B10SMN1; SMN2RAB9ANPC1LMNA
SCHEMBL67045 0.93 HSD17B10 (0.69) HSD17B10SMN1; SMN2RAB9ANPC1LMNA
SCHEMBL27877016 0.93 HSD17B10 (0.69) HSD17B10SMN1; SMN2RAB9ANPC1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026102082-A1 ALKYLPHENYL SUBSTITUTED COMPOUNDS, COMPOSITIONS AND METHODS OF USE DEEP APPLE THERAPEUTICS, INC. (US) 2026-05-15 — — WO disclosed
US-20260132119-A1 Alkylphenyl Substituted Compounds, Compositions and Methods of Use DEEP APPLE THERAPEUTICS, INC. (US) 2026-05-14 — — US disclosed
EP-4695260-A1 KRAS MODULATING COMPOUNDS GILEAD SCIENCES, INC. (US) 2026-02-18 — — EP disclosed
EP-4695236-A1 SUBSTITUTED PHENYL-PIPERAZINYL BASED MODULATORS FOR THE TREATMENT OF DISEASE Soley Therapeutics, Inc. (US) 2026-02-18 — — EP disclosed
US-12338230-B2 Aryl, heteroaryl, and heterocyclic compounds for treatment of immune and inflammatory disorders ACHILLION PHARMACEUTICALS, INC. (US) 2025-06-24 — — US disclosed
US-20250034166-A1 POLYCYCLIC FUSED RING DERIVATIVES AND USE THEREOF JACOBIO PHARMACEUTICALS CO., LTD. (CN) 2025-01-30 — — US disclosed
US-20240383922-A1 KRAS Modulating Compounds GILEAD SCIENCES, INC. 2024-11-21 — — US disclosed
WO-2024216094-A1 SUBSTITUTED PHENYL-PIPERAZINYL BASED MODULATORS FOR THE TREATMENT OF DISEASE SOLEY THERAPEUTICS, INC. (US) 2024-10-17 — — WO disclosed
WO-2024215754-A1 KRAS MODULATING COMPOUNDS GILEAD SCIENCES, INC. (US) 2024-10-17 — — WO disclosed
WO-2024178304-A1 KRAS MODULATORS ALTEROME THERAPEUTICS, INC. (US) 2024-08-29 — — WO disclosed
CN-1327766-C Compounds, compositions, and methods for controlling biofilms PROCTER & GAMBLE (US) 2007-07-25 — — CN disclosed
CN-1307875-C Compounds, compositions and methods for controlling biofilms PROCTER & GAMBLE (US) 2007-04-04 — — CN disclosed
US-20060165648-A1 Compounds, compositions, and methods for controlling biofilms DEGENHARDT CHARLES R 2006-07-27 — — US disclosed
US-7018642-B2 Compounds, compositions, and methods for controlling biofilms THE PROCTER & GAMBLE COMPANY (US) 2006-03-28 — — US disclosed
CN-1699545-A Apparatus and method for controlling biofilms PROCTER & GAMBLE (US) 2005-11-23 — — CN disclosed
CN-1689405-A Compounds, compositions, and methods for controlling biofilms PROCTER & GAMBLE (US) 2005-11-02 — — CN disclosed
CN-1527876-A Compounds, compositions and methods for controlling biofilms — 2004-09-08 — — CN disclosed
EP-1381668-A1 COMPOUNDS, COMPOSITIONS, AND METHODS FOR CONTROLLING BIOFILMS THE PROCTER & GAMBLE COMPANY (US) 2004-01-21 — — EP disclosed
US-20030105072-A1 Compounds, compositions, and methods for controlling biofilms THE PROCTER & GAMBLE COMPANY 2003-06-05 — — US disclosed
WO-2002088298-A1 COMPOUNDS, COMPOSITIONS, AND METHODS FOR CONTROLLING BIOFILMS THE PROCTER & GAMBLE COMPANY (US) 2002-11-07 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240383922-A1 KRAS Modulating Compounds KRAS, NRAS, HRAS HSD17B10 4557/4885SMN1; SMN2 3325/4885RAB9A 77/4885
US-12338230-B2 Aryl, heteroaryl, and heterocyclic compounds for treatment of immune and inflammatory disorders CFD, TFPI, CFH HSD17B10 1764/4885SMN1; SMN2 4688/4885RAB9A 2300/4885
US-20250034166-A1 POLYCYCLIC FUSED RING DERIVATIVES AND USE THEREOF KRAS, NRAS, HRAS HSD17B10 3868/4885SMN1; SMN2 4125/4885RAB9A 70/4885
US-20260132119-A1 Alkylphenyl Substituted Compounds, Compositions and Methods of Use GIPR, MC2R, GRPR HSD17B10 1168/4885SMN1; SMN2 881/4885RAB9A 2345/4885
US-20060165648-A1 Compounds, compositions, and methods for controlling biofilms BMP2, BMP1, BMP4 HSD17B10 3332/4885SMN1; SMN2 4869/4885RAB9A 2871/4885
US-20030105072-A1 Compounds, compositions, and methods for controlling biofilms BMP2, BMP1, BMP4 HSD17B10 3332/4885SMN1; SMN2 4869/4885RAB9A 2871/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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