SCHEMBL222955

SCHEMBL222955

CC(C)(C)OC(=O)N1CCCCCC1C(=O)O

nearest known ligand 0.62

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 2/20 0.62
SMN1; SMN2 Q16637 2/20 0.54
RAB9A P51151 1/20 0.50
NPC1 O15118 1/20 0.48
LMNA P02545 2/20 0.48
HPGD P15428 1/20 0.48
CYP2C19 P33261 1/20 0.48
ALDH1A1 P00352 2/20 0.47
NPSR1 Q6W5P4 1/20 0.46
EPHX1 P07099 1/20 0.46
UCHL1 P09936 1/20 0.44
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5898691 1.00 HSD17B10 (0.62) HSD17B10SMN1; SMN2RAB9ANPC1LMNA
SCHEMBL18358031 1.00 HSD17B10 (0.62) HSD17B10SMN1; SMN2RAB9ANPC1LMNA
SCHEMBL77858 0.98 HSD17B10 (0.63) HSD17B10SMN1; SMN2RAB9ANPC1LMNA
SCHEMBL65491 0.98 HSD17B10 (0.63) HSD17B10SMN1; SMN2RAB9ANPC1LMNA
SCHEMBL65490 0.98 HSD17B10 (0.63) HSD17B10SMN1; SMN2RAB9ANPC1LMNA
SCHEMBL85536 0.93 HSD17B10 (0.69) HSD17B10SMN1; SMN2RAB9ANPC1LMNA
SCHEMBL67044 0.93 HSD17B10 (0.69) HSD17B10SMN1; SMN2RAB9ANPC1LMNA
SCHEMBL6219872 0.93 HSD17B10 (0.69) HSD17B10SMN1; SMN2RAB9ANPC1LMNA
SCHEMBL67045 0.93 HSD17B10 (0.69) HSD17B10SMN1; SMN2RAB9ANPC1LMNA
SCHEMBL27877016 0.93 HSD17B10 (0.69) HSD17B10SMN1; SMN2RAB9ANPC1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 142 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026102082-A1 ALKYLPHENYL SUBSTITUTED COMPOUNDS, COMPOSITIONS AND METHODS OF USE DEEP APPLE THERAPEUTICS, INC. (US) 2026-05-15 WO disclosed
US-20260132119-A1 Alkylphenyl Substituted Compounds, Compositions and Methods of Use DEEP APPLE THERAPEUTICS, INC. (US) 2026-05-14 US disclosed
EP-4735438-A2 HETEROBIFUNCTIONAL COMPOUNDS FOR THE DEGRADATION OF KRAS Merck Patent GmbH (DE) 2026-05-06 EP disclosed
US-20260103459-A1 SUBSTITUTED AZACYLES AS TRPM8 MODULATORS GIVAUDAN SA (CH) 2026-04-16 US disclosed
EP-4709376-A1 FUSED RING KRAS INHIBITORS FOR TREATING DISEASE Blossomhill Therapeutics, Inc. (US) 2026-03-18 EP disclosed
US-12528801-B2 Substituted azacyles as TRPM8 modulators GIVAUDAN SA (CH) 2026-01-20 US disclosed
US-12338230-B2 Aryl, heteroaryl, and heterocyclic compounds for treatment of immune and inflammatory disorders ACHILLION PHARMACEUTICALS, INC. (US) 2025-06-24 US disclosed
US-12291516-B2 Substituted 1-amino-1H-imidazole-5-carboxamide as Bruton's tyrosine kinase inhibitors HENAN ZHIWEI BIOMEDICINE CO., LTD. (CN) 2025-05-06 US disclosed
CN-114555594-B Substituted azacycles as TRMP modulators 奇华顿股份有限公司 2025-03-18 CN disclosed
US-20250034166-A1 POLYCYCLIC FUSED RING DERIVATIVES AND USE THEREOF JACOBIO PHARMACEUTICALS CO., LTD. (CN) 2025-01-30 US disclosed
US-8084448-B2 Organic compounds NOVARTIS AG (CH) 2011-12-27 US disclosed
US-20110312944-A1 Heterocyclic Compounds Which Modulate The CB2 Receptor BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2011-12-22 US disclosed
US-20090181928-A1 ORGANIC COMPOUNDS NOVARTIS AG (CH) 2009-07-16 US disclosed
EP-2038267-A2 THIADIAZOLIDINONE INHIBITORS OF PTPASE Novartis AG (CH) 2009-03-25 EP disclosed
WO-2007115058-A2 THIADIAZOLIDINONE INHIBITORS OF PTPASE NOVARTIS AG (CH) 2007-10-11 WO disclosed
US-20060165648-A1 Compounds, compositions, and methods for controlling biofilms DEGENHARDT CHARLES R 2006-07-27 US disclosed
US-7018642-B2 Compounds, compositions, and methods for controlling biofilms THE PROCTER & GAMBLE COMPANY (US) 2006-03-28 US disclosed
EP-1381668-A1 COMPOUNDS, COMPOSITIONS, AND METHODS FOR CONTROLLING BIOFILMS THE PROCTER & GAMBLE COMPANY (US) 2004-01-21 EP disclosed
US-20030105072-A1 Compounds, compositions, and methods for controlling biofilms THE PROCTER & GAMBLE COMPANY 2003-06-05 US disclosed
WO-2002088298-A1 COMPOUNDS, COMPOSITIONS, AND METHODS FOR CONTROLLING BIOFILMS THE PROCTER & GAMBLE COMPANY (US) 2002-11-07 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260103459-A1 SUBSTITUTED AZACYLES AS TRPM8 MODULATORS TRPM8, TRPM7, TRPM5 HSD17B10 3385/4885SMN1; SMN2 2680/4885RAB9A 1602/4885
US-12338230-B2 Aryl, heteroaryl, and heterocyclic compounds for treatment of immune and inflammatory disorders CFD, TFPI, CFH HSD17B10 1764/4885SMN1; SMN2 4688/4885RAB9A 2300/4885
US-20110312944-A1 Heterocyclic Compounds Which Modulate The CB2 Receptor CNR2, CNR1, OPRL1 HSD17B10 2211/4885SMN1; SMN2 4609/4885RAB9A 2445/4885
US-12291516-B2 Substituted 1-amino-1H-imidazole-5-carboxamide as Bruton's tyrosine kinase inhibitors BTK, SYK, TYK2 HSD17B10 4431/4885SMN1; SMN2 2857/4885RAB9A 2829/4885
US-20250034166-A1 POLYCYCLIC FUSED RING DERIVATIVES AND USE THEREOF KRAS, NRAS, HRAS HSD17B10 3868/4885SMN1; SMN2 4125/4885RAB9A 70/4885
US-20090181928-A1 ORGANIC COMPOUNDS PTPRS, PTPRO, PTPRC HSD17B10 794/4885SMN1; SMN2 1590/4885RAB9A 3949/4885
US-12528801-B2 Substituted azacyles as TRPM8 modulators TRPM8, TRPM7, TRPM4 HSD17B10 2254/4885SMN1; SMN2 2759/4885RAB9A 2152/4885
US-20260132119-A1 Alkylphenyl Substituted Compounds, Compositions and Methods of Use GIPR, MC2R, GRPR HSD17B10 1168/4885SMN1; SMN2 881/4885RAB9A 2345/4885
US-20060165648-A1 Compounds, compositions, and methods for controlling biofilms BMP2, BMP1, BMP4 HSD17B10 3332/4885SMN1; SMN2 4869/4885RAB9A 2871/4885
US-20030105072-A1 Compounds, compositions, and methods for controlling biofilms BMP2, BMP1, BMP4 HSD17B10 3332/4885SMN1; SMN2 4869/4885RAB9A 2871/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.