Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.44 |
| ▸ | HPGD | P15428 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | SLC34A1 | Q06495 | 2/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9753208 | 0.90 | CDC7 (0.44) | ALDH1A1KDM4EHPGDMEN1GAA | |
| SCHEMBL9752865 | 0.86 | ALDH1A1 (0.49) | ALDH1A1KDM4EHPGDMEN1GAA | |
| SCHEMBL9753377 | 0.83 | EGFR (0.44) | ALDH1A1KDM4EHPGDMEN1GAA | |
| SCHEMBL9753347 | 0.81 | PTPRC (0.43) | ALDH1A1KDM4EHPGDMEN1GAA | |
| SCHEMBL9753865 | 0.80 | EGFR (0.59) | ALDH1A1KDM4EHPGDMEN1GAA | |
| SCHEMBL5093057 | 0.80 | ALDH1A1 (0.52) | ALDH1A1KDM4EHPGDMEN1GAA | |
| SCHEMBL29939370 | 0.79 | SLC34A1 (0.45) | ALDH1A1KDM4EHPGDMEN1GAA | |
| SCHEMBL9753098 | 0.78 | GCGR (0.40) | EGFRMIF | |
| SCHEMBL9752941 | 0.76 | ALDH1A1 (0.35) | ALDH1A1EGFR | |
| SCHEMBL31277518 | 0.76 | EGFR (0.56) | ALDH1A1KDM4EHPGDMEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991018903-A1 | PYRROLOPYRIDAZINE COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-12-12 | — | — | WO | disclosed |