Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.40 |
| ▸ | HPGD | P15428 | 7/20 | 0.40 |
| ▸ | MEN1 | O00255 | 5/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | GAA | P10253 | 5/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | SPR | P35270 | 2/20 | 0.37 |
| ▸ | MIF | P14174 | 2/20 | 0.36 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 3/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9753347 | 0.91 | PTPRC (0.43) | EGFRALDH1A1KDM4EHPGDMEN1 | |
| SCHEMBL9752865 | 0.89 | ALDH1A1 (0.49) | EGFRALDH1A1KDM4EHPGDMEN1 | |
| SCHEMBL9753865 | 0.85 | EGFR (0.59) | EGFRALDH1A1KDM4EHPGDMEN1 | |
| SCHEMBL9752829 | 0.83 | ALDH1A1 (0.44) | EGFRALDH1A1KDM4EHPGDMEN1 | |
| SCHEMBL5093057 | 0.81 | ALDH1A1 (0.52) | EGFRALDH1A1KDM4EHPGDMEN1 | |
| SCHEMBL9753208 | 0.80 | CDC7 (0.44) | EGFRALDH1A1KDM4EHPGDMEN1 | |
| SCHEMBL9753346 | 0.78 | GCGR (0.39) | EGFRALDH1A1MEN1KMT2AMIF | |
| SCHEMBL27438905 | 0.76 | RORC (0.38) | EGFRALDH1A1MEN1KMT2AMIF | |
| SCHEMBL9753354 | 0.76 | PTGS2 (0.34) | EGFRALDH1A1MEN1KMT2AMIF | |
| SCHEMBL3821849 | 0.74 | ALDH1A1 (0.49) | EGFRALDH1A1KDM4EHPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991018903-A1 | PYRROLOPYRIDAZINE COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-12-12 | — | — | WO | disclosed |