Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 3/20 | 0.40 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
| ▸ | MAP4K4 | O95819 | 4/20 | 0.33 |
| ▸ | CSNK1D | P48730 | 4/20 | 0.33 |
| ▸ | MINK1 | Q8N4C8 | 4/20 | 0.33 |
| ▸ | PRKD2 | Q9BZL6 | 4/20 | 0.33 |
| ▸ | PRKD3 | O94806 | 3/20 | 0.33 |
| ▸ | MAPK9 | P45984 | 3/20 | 0.33 |
| ▸ | RORC | P51449 | 2/20 | 0.33 |
| ▸ | DHODH | Q02127 | 1/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.32 |
| ▸ | EGFR | P00533 | 3/20 | 0.32 |
| ▸ | GSK3B | P49841 | 2/20 | 0.32 |
| ▸ | RAF1 | P04049 | 1/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9753419 | 0.89 | GRM2 (0.36) | GCGRGRM2MAPK14 | |
| SCHEMBL9753170 | 0.83 | MAPK14 (0.44) | GCGRMAPK14EGFRGSK3BRAF1 | |
| SCHEMBL9753346 | 0.81 | GCGR (0.39) | GCGRTGFBR1GABRA5MAPK14EGFR | |
| SCHEMBL9752941 | 0.80 | ALDH1A1 (0.35) | MAP4K4CSNK1DMINK1PRKD2PRKD3 | |
| SCHEMBL9753002 | 0.78 | TGFBR1 (0.36) | TGFBR1MAPK14EGFRADORA2AADORA1 | |
| SCHEMBL9752919 | 0.77 | SMN1; SMN2 (0.43) | GCGREGFRADORA2AADORA1MIF | |
| SCHEMBL9753497 | 0.76 | MAPK14 (0.31) | MAP4K4CSNK1DMINK1PRKD2PRKD3 | |
| SCHEMBL9753499 | 0.76 | MAPK14 (0.31) | MAP4K4CSNK1DMINK1PRKD2PRKD3 | |
| SCHEMBL9753501 | 0.73 | HMGCR (0.45) | ADORA3 | |
| SCHEMBL9753024 | 0.72 | HMGCR (0.35) | ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991018903-A1 | PYRROLOPYRIDAZINE COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-12-12 | — | — | WO | disclosed |