Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC7 | O00311 | 1/20 | 0.44 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.44 |
| ▸ | NR3C2 | P08235 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | SPR | P35270 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9752829 | 0.90 | ALDH1A1 (0.44) | NR3C2KDM4EALDH1A1HPGDMEN1 | |
| SCHEMBL27347534 | 0.86 | RORC (0.37) | NR3C2ALDH1A1MEN1KMT2ANPSR1 | |
| SCHEMBL9752865 | 0.84 | ALDH1A1 (0.49) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL9753347 | 0.83 | PTPRC (0.43) | NR3C2KDM4EALDH1A1HPGDMEN1 | |
| SCHEMBL9753377 | 0.80 | EGFR (0.44) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL9753419 | 0.79 | GRM2 (0.36) | CDC7DBF4 | |
| SCHEMBL9753865 | 0.79 | EGFR (0.59) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL5093057 | 0.78 | ALDH1A1 (0.52) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL9753400 | 0.77 | TP53 (0.36) | ALDH1A1MEN1KMT2AEGFRLMNA | |
| SCHEMBL9752977 | 0.74 | TP53 (0.34) | NR3C2SPR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991018903-A1 | PYRROLOPYRIDAZINE COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-12-12 | — | — | WO | disclosed |