Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.43 |
| ▸ | NPY1R | P25929 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9752704 | 0.89 | MAPT (0.42) | LMNAMAPTPOLBPKMKDM4E | |
| SCHEMBL4862038 | 0.83 | TAAR1 (0.40) | LMNANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL10418940 | 0.80 | DDB1 (0.42) | ALDH1A1 | |
| SCHEMBL9752802 | 0.76 | ARG1 (0.42) | LMNAMAPTPOLBKDM4EKMT2A | |
| SCHEMBL17350953 | 0.74 | SLC18A2 (0.44) | — | |
| SCHEMBL9753055 | 0.74 | ARG1 (0.41) | LMNAMAPTPOLBKMT2AMEN1 | |
| SCHEMBL10418525 | 0.73 | RAB9A (0.40) | LMNAMAPTPOLBKDM4ENPC1 | |
| SCHEMBL28592319 | 0.72 | ARG1 (0.39) | POLBKDM4EKMT2AMEN1ALDH1A1 | |
| SCHEMBL4558511 | 0.71 | MEN1 (0.40) | KMT2AMEN1OPRM1 | |
| SCHEMBL545631 | 0.71 | L3MBTL1 (0.41) | LMNAMAPTPOLBPKMKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991007378-A1 | CYCLOALKYL-SUBSTITUTED GLUTARAMIDE DIURETIC AGENTS | PFIZER LIMITED (GB) | 1991-05-30 | — | — | WO | disclosed |