Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.35 |
| ▸ | TGFBR2 | P37173 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9753687 | 0.83 | ALDH1A1 (0.39) | GCGRALDH1A1KDM4EGAAALOX15 | |
| SCHEMBL9753282 | 0.81 | CACNA1F (0.46) | GCGRALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL9753309 | 0.81 | MAPK14 (0.43) | GCGRTGFBR1TGFBR2 | |
| SCHEMBL9753771 | 0.81 | GCGR (0.40) | GCGRTGFBR1TGFBR2 | |
| SCHEMBL27438907 | 0.81 | ALDH1A1 (0.37) | GCGRALDH1A1KDM4EGAAALOX15 | |
| SCHEMBL9753310 | 0.81 | ALDH1A1 (0.37) | GCGRALDH1A1KDM4EGAAALOX15 | |
| SCHEMBL9753336 | 0.80 | MAPK14 (0.42) | GCGRTGFBR1TGFBR2 | |
| SCHEMBL9752952 | 0.80 | GCGR (0.39) | GCGRTGFBR1TGFBR2 | |
| SCHEMBL9752950 | 0.80 | GABRA5 (0.34) | GCGRALDH1A1LMNAGABRA5MAPT | |
| SCHEMBL9753125 | 0.79 | GCGR (0.37) | GCGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991018903-A1 | PYRROLOPYRIDAZINE COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-12-12 | — | — | WO | disclosed |