Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA5 | P31644 | 11/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | GCGR | P47871 | 1/20 | 0.32 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.32 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9753073 | 0.85 | L3MBTL1 (0.33) | GABRA5GABRG2GABRB3 | |
| SCHEMBL9752951 | 0.81 | LMNA (0.36) | GABRA5ALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL9753038 | 0.80 | GCGR (0.47) | GABRA5ALDH1A1LMNAMAPTTP53 | |
| SCHEMBL9753687 | 0.72 | ALDH1A1 (0.39) | ALDH1A1SMN1; SMN2LMNAMAPTTP53 | |
| SCHEMBL9753310 | 0.70 | ALDH1A1 (0.37) | GABRA5ALDH1A1SMN1; SMN2LMNAMAPT | |
| SCHEMBL27438907 | 0.70 | ALDH1A1 (0.37) | GABRA5ALDH1A1SMN1; SMN2LMNAMAPT | |
| SCHEMBL9879298 | 0.69 | ADORA3 (0.41) | GABRA5ALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL9265733 | 0.67 | GCGR (0.50) | ALDH1A1MEN1KMT2AGCGR | |
| SCHEMBL6958480 | 0.67 | GCGR (0.61) | GCGR | |
| SCHEMBL9753762 | 0.66 | HMGCR (0.39) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991018903-A1 | PYRROLOPYRIDAZINE COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-12-12 | — | — | WO | disclosed |