Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 13/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.36 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.34 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.34 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27529264 | 0.80 | PPP1CA (0.37) | MAPK14CSNK1DCSNK1E | |
| SCHEMBL9753384 | 0.79 | ALDH1A1 (0.36) | MAPK14 | |
| SCHEMBL9753170 | 0.78 | MAPK14 (0.44) | GCGRMAPK14 | |
| SCHEMBL9753668 | 0.77 | GRM6 (0.41) | TGFBR1 | |
| SCHEMBL9753232 | 0.75 | MAPK14 (0.33) | MAPK14 | |
| SCHEMBL9753231 | 0.75 | MAPK14 (0.33) | MAPK14 | |
| SCHEMBL9753336 | 0.75 | MAPK14 (0.42) | GCGRMAPK14CSNK1DCSNK1ETGFBR1 | |
| SCHEMBL9753293 | 0.74 | GCGR (0.41) | GCGRCSNK1DCSNK1E | |
| SCHEMBL9752988 | 0.71 | HMGCR (0.40) | — | |
| SCHEMBL9752987 | 0.71 | HMGCR (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991018903-A1 | PYRROLOPYRIDAZINE COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-12-12 | — | — | WO | disclosed |
| CN-1056690-A | PYRROLOPYRIDAZINE COMPOUNDS | FUJISAWA PHARMACEUTICAL CO (JP) | 1991-12-04 | — | — | CN | disclosed |