Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPP1CA | P62136 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | DHODH | Q02127 | 6/20 | 0.35 |
| ▸ | MARS1 | P56192 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.32 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.32 |
| ▸ | SRC | P12931 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | HMGCR | P04035 | 1/20 | 0.32 |
| ▸ | RORC | P51449 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9752981 | 0.86 | DGAT1 (0.40) | KMT2AMEN1KDM4E | |
| SCHEMBL9753357 | 0.80 | PTGER1 (0.36) | KMT2AMEN1DHODHKDM5BKDM4E | |
| SCHEMBL27529264 | 0.79 | PPP1CA (0.37) | PPP1CAKMT2AMEN1ATMDHODH | |
| SCHEMBL27352605 | 0.79 | KDM4E (0.38) | KMT2AMEN1DHODHPPARAKDM5B | |
| SCHEMBL9752966 | 0.75 | DGAT1 (0.41) | KMT2AMEN1KDM4E | |
| SCHEMBL27349905 | 0.75 | PTGER1 (0.38) | KMT2AMEN1DHODHKDM5BKDM4E | |
| SCHEMBL9753363 | 0.71 | DHODH (0.38) | DHODHKDM5BKDM4ECSNK1DCSNK1E | |
| SCHEMBL9752927 | 0.71 | PTGER1 (0.41) | KMT2AMEN1DHODHKDM4EHMGCR | |
| SCHEMBL9752965 | 0.69 | MAPK14 (0.43) | KMT2AMEN1DHODHKDM5B | |
| SCHEMBL9753008 | 0.67 | PTGS2 (0.32) | KMT2AKDM5B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991018903-A1 | PYRROLOPYRIDAZINE COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-12-12 | — | — | WO | disclosed |