SCHEMBL9753412

SCHEMBL9753412

Nc1cc(Cl)cc(CP(=O)(O)O)n1

nearest known ligand 0.44

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
PGK1 P00558 1/20 0.44
PGK2 P07205 1/20 0.44
GRIN2D O15399 1/20 0.36
GRIN3B O60391 1/20 0.36
GRIN1 Q05586 1/20 0.36
GRIN2A Q12879 1/20 0.36
GRIN2B Q13224 1/20 0.36
GRIN2C Q14957 1/20 0.36
GRIN3A Q8TCU5 1/20 0.36
SMN1; SMN2 Q16637 2/20 0.35
HTT P42858 1/20 0.33
KMT2A Q03164 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9753555 0.75 PGK1 (0.41) PGK1PGK2SMN1; SMN2KMT2A
SCHEMBL21355550 0.72 NOTUM (0.39) KMT2A
SCHEMBL4435970 0.71 NOS2 (0.61) SMN1; SMN2KMT2A
SCHEMBL3661086 0.68
SCHEMBL2654478 0.68 PGK1 (0.44) PGK1PGK2KMT2A
SCHEMBL8608767 0.68 MEN1 (0.31) KMT2A
SCHEMBL9753503 0.67 PGK1 (0.41) PGK1PGK2HTTKMT2A
Hydrochloric Acid SCHEMBL3136371 0.67 PGK1 (0.42) PGK1PGK2KMT2A
SCHEMBL26262569 0.67 NOS3 (0.41)
SCHEMBL21354821 0.67 ADH1B (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1991008211-A1 IMIDAZO[1,2-a]PYRIDINYLALKYL COMPOUNDS FOR TREATMENT OF NEUROTOXIC INJURY G.D. SEARLE & CO. (US) 1991-06-13 WO disclosed