Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.44 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.43 |
| ▸ | KCNK10 | P57789 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.43 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.42 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.41 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.41 |
| ▸ | ITGAV | P06756 | 1/20 | 0.41 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.41 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9536551 | 1.00 | KMT2A (0.51) | KMT2AMEN1HDAC1NPSR1KCNK2 | |
| SCHEMBL8634319 | 0.82 | GAA (0.45) | NPSR1SMN1; SMN2 | |
| SCHEMBL9069914 | 0.82 | CA2 (0.49) | ALDH1A1 | |
| SCHEMBL8635668 | 0.77 | PREP (0.64) | KMT2APOLBCYP2C19ALDH1A1 | |
| SCHEMBL9538915 | 0.77 | PREP (0.64) | KMT2APOLBCYP2C19ALDH1A1 | |
| SCHEMBL18386410 | 0.72 | NPSR1 (0.67) | KMT2AMEN1HDAC1NPSR1ALDH1A1 | |
| SCHEMBL11783834 | 0.71 | ITGB3 (0.57) | KMT2ASMN1; SMN2ITGB3ITGB1ITGAV | |
| SCHEMBL11783845 | 0.71 | ITGB3 (0.57) | KMT2ASMN1; SMN2ITGB3ITGB1ITGAV | |
| SCHEMBL12857367 | 0.68 | PYGL (0.46) | KMT2APOLBSMN1; SMN2ITGB3ITGB1 | |
| SCHEMBL29039362 | 0.67 | LMNA (0.39) | CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991018891-A1 | AROMATIC PYRROLIDINE AND THIAZOLIDINE AMIDES | PFIZER INC. (US) | 1991-12-12 | — | — | WO | disclosed |