Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RBP4 | P02753 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.37 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.37 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | RXRA | P19793 | 1/20 | 0.35 |
| ▸ | RXRB | P28702 | 1/20 | 0.35 |
| ▸ | RXRG | P48443 | 1/20 | 0.35 |
| ▸ | CETP | P11597 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9306266 | 0.81 | RAB9A (0.39) | RBP4ALDH1A1TDP1TSHRATM | |
| SCHEMBL7030333 | 0.77 | ALDH1A1 (0.43) | RBP4ALDH1A1TDP1TSHRATM | |
| SCHEMBL6248477 | 0.76 | MTNR1A (0.50) | TSHRPTGS2CA2KDM4ECA12 | |
| SCHEMBL29053925 | 0.76 | ALDH1A1 (0.38) | ALDH1A1TDP1TSHRPTGS2CA2 | |
| SCHEMBL6655975 | 0.76 | THRB (0.39) | ALDH1A1TDP1TSHRPTGS2CA2 | |
| SCHEMBL12379210 | 0.76 | CA2 (0.53) | RBP4ALDH1A1TDP1TSHRATM | |
| SCHEMBL13145616 | 0.75 | TDP1 (0.41) | RBP4ALDH1A1TDP1TSHRATM | |
| SCHEMBL9632576 | 0.74 | IDO1 (0.40) | ALDH1A1PTGS2CA2KDM4EGAA | |
| SCHEMBL17644164 | 0.74 | ALDH1A1 (0.38) | RBP4ALDH1A1TDP1TSHRATM | |
| SCHEMBL13145618 | 0.72 | TDP1 (0.39) | RBP4ALDH1A1TDP1TSHRATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991009598-A1 | AZAOXINDOLE DERIVATIVES | PFIZER INC. (US) | 1991-07-11 | — | — | WO | disclosed |