Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 3/20 | 0.54 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.48 |
| ▸ | TRPM8 | Q7Z2W7 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.44 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.44 |
| ▸ | CDC7 | O00311 | 1/20 | 0.43 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9754402 | 0.80 | ALOX5 (0.56) | ALOX5KDM4ENPC1LMNATP53 | |
| SCHEMBL9630221 | 0.78 | TRPM8 (0.54) | ALOX5PTGDR2TRPM8KDM4ECDC7 | |
| SCHEMBL9629404 | 0.74 | TRPM8 (0.59) | ALOX5TRPM8CDC7DBF4 | |
| SCHEMBL9754206 | 0.72 | ALOX5 (0.53) | ALOX5TRPM8NPC1LMNACYP1A2 | |
| SCHEMBL9630543 | 0.72 | TRPM8 (0.57) | ALOX5TRPM8CDC7DBF4 | |
| SCHEMBL9754018 | 0.71 | ALOX5 (0.52) | ALOX5TRPM8NPC1LMNACYP1A2 | |
| Potassium SCHEMBL9754024 | 0.71 | ALOX5 (0.52) | ALOX5TRPM8NPC1LMNACYP1A2 | |
| SCHEMBL9628554 | 0.71 | TRPM8 (0.62) | ALOX5PTGDR2TRPM8MAPTCDC7 | |
| SCHEMBL9629437 | 0.71 | ALOX5 (1.00) | ALOX5PTGDR2TRPM8KDM4ENPC1 | |
| SCHEMBL15662821 | 0.67 | CYP1A2 (0.61) | KDM4ENPC1LMNATP53CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991008744-A1 | THIAZOLE LIPOXYGENASE-INHIBITING COMPOUNDS DERIVED FROM NON-STEROIDAL ANTIINFLAMMATORY CARBOXYLIC ACIDS | ABBOTT LABORATORIES (US) | 1991-06-27 | — | — | WO | disclosed |