Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 7/20 | 0.48 |
| ▸ | ACACB | O00763 | 2/20 | 0.39 |
| ▸ | ACACA | Q13085 | 2/20 | 0.39 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.37 |
| ▸ | BAX | Q07812 | 1/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9754071 | 0.83 | ALOX5 (0.53) | ALOX5 | |
| SCHEMBL9754000 | 0.81 | ALOX5 (0.46) | ALOX5 | |
| SCHEMBL9754190 | 0.74 | ALOX5 (0.49) | ALOX5 | |
| SCHEMBL25969457 | 0.71 | LTA4H (0.57) | ACACBACACASRD5A2LTA4HNR1H2 | |
| SCHEMBL9754025 | 0.68 | ALOX5 (0.43) | ALOX5 | |
| SCHEMBL9803529 | 0.68 | ALOX5 (0.43) | ALOX5 | |
| SCHEMBL9629437 | 0.65 | ALOX5 (1.00) | ALOX5 | |
| SCHEMBL9629574 | 0.65 | ALOX5 (1.00) | ALOX5 | |
| SCHEMBL4368301 | 0.64 | SRD5A2 (0.55) | ACACBACACASRD5A2LTA4HNR1H2 | |
| SCHEMBL1954803 | 0.64 | ALOX5 (0.66) | ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5032588-A | Non-steroidal antiinflammatory | ABBOTT LABORATORIES (US) | 1991-07-16 | — | — | US | disclosed |
| WO-1991008744-A1 | THIAZOLE LIPOXYGENASE-INHIBITING COMPOUNDS DERIVED FROM NON-STEROIDAL ANTIINFLAMMATORY CARBOXYLIC ACIDS | ABBOTT LABORATORIES (US) | 1991-06-27 | — | — | WO | disclosed |