Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | LSS | P48449 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | DRD4 | P21917 | 1/20 | 0.50 |
| ▸ | GPR183 | P32249 | 1/20 | 0.49 |
| ▸ | FAAH | O00519 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2325333 | 0.83 | LMNA (0.65) | ALDH1A1MEN1KMT2APOLB | |
| SCHEMBL1134937 | 0.82 | SIGMAR1 (0.72) | SIGMAR1ALDH1A1KMT2APOLBDRD4 | |
| SCHEMBL11529484 | 0.80 | SIGMAR1 (0.58) | SIGMAR1KDM4EALDH1A1LSSMEN1 | |
| SCHEMBL5540357 | 0.79 | KDM4E (0.65) | SIGMAR1KDM4EALDH1A1FAAH | |
| SCHEMBL5542250 | 0.78 | FAAH (0.51) | SIGMAR1KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL23851111 | 0.77 | ALDH1A1 (0.87) | SIGMAR1KDM4EALDH1A1LSSMEN1 | |
| SCHEMBL7937990 | 0.77 | ALDH1A1 (0.95) | SIGMAR1KDM4EALDH1A1LSSPOLB | |
| SCHEMBL4054721 | 0.77 | SIGMAR1 (0.62) | SIGMAR1ALDH1A1POLBDRD4 | |
| SCHEMBL10502663 | 0.76 | SIGMAR1 (0.68) | SIGMAR1KDM4EALDH1A1LSSMEN1 | |
| SCHEMBL12717312 | 0.76 | ALDH1A1 (0.71) | SIGMAR1KDM4EALDH1A1LSSMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991013868-A1 | PHENYLTHIOALKYLCARBOXYLIC ACID DERIVATIVES, METHOD FOR PREPARING THEM AND DRUGS CONTAINING THESE COMPOUNDS | BOEHRINGER MANNHEIM GMBH (DE) | 1991-09-19 | — | — | WO | disclosed |