Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 9/20 | 0.53 |
| ▸ | NPC1 | O15118 | 8/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.53 |
| ▸ | ACHE | P22303 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | CA1 | P00915 | 3/20 | 0.51 |
| ▸ | CA2 | P00918 | 3/20 | 0.51 |
| ▸ | CA7 | P43166 | 3/20 | 0.51 |
| ▸ | CA9 | Q16790 | 3/20 | 0.51 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5681767 | 0.81 | RAB9A (0.73) | RAB9ANPC1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL5747563 | 0.77 | ACHE (0.52) | ACHEHDAC1HDAC6 | |
| SCHEMBL9812935 | 0.77 | KMT2A (0.60) | RAB9ANPC1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL3578191 | 0.77 | KMT2A (0.56) | RAB9ANPC1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL9100881 | 0.76 | MEN1 (0.66) | RAB9ANPC1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL3577619 | 0.76 | TRPV1 (0.69) | RAB9ANPC1MEN1KMT2AHDAC3 | |
| SCHEMBL10160200 | 0.75 | KDM5B (0.69) | RAB9ANPC1SMN1; SMN2MAPTHDAC3 | |
| SCHEMBL13895347 | 0.74 | RAB9A (0.65) | RAB9ANPC1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL28699553 | 0.74 | RAB9A (0.83) | RAB9ANPC1MAPTHDAC3HDAC4 | |
| SCHEMBL10160158 | 0.74 | KDM4E (0.66) | RAB9ANPC1SMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991013868-A1 | PHENYLTHIOALKYLCARBOXYLIC ACID DERIVATIVES, METHOD FOR PREPARING THEM AND DRUGS CONTAINING THESE COMPOUNDS | BOEHRINGER MANNHEIM GMBH (DE) | 1991-09-19 | — | — | WO | disclosed |