Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | KCNN4 | O15554 | 3/20 | 0.36 |
| ▸ | KIF11 | P52732 | 2/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.30 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.30 |
| ▸ | DHFR | P00374 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8805721 | 0.87 | TRPA1 (0.39) | TRPA1ATMKCNN4KIF11GABRA1 | |
| SCHEMBL3404421 | 0.86 | MAPK1 (0.37) | KCNN4KIF11GABRA1GABRB2MAPK1 | |
| SCHEMBL28762342 | 0.80 | GABRA1 (0.40) | TRPA1ATMKCNN4KIF11GABRA1 | |
| Methoxytriphenylmethane SCHEMBL9103 | 0.75 | MAPK1 (0.48) | KCNN4KIF11MAPK1CES1CYP19A1 | |
| SCHEMBL5598485 | 0.75 | ESR1 (0.44) | TRPA1ATMKCNN4KIF11GABRA1 | |
| SCHEMBL3740131 | 0.75 | ESR1 (0.42) | TRPA1ATMKCNN4KIF11GABRA1 | |
| SCHEMBL11524886 | 0.75 | TRPA1 (0.41) | TRPA1ATMKCNN4KIF11GABRA1 | |
| SCHEMBL4615965 | 0.75 | KCNN4 (0.46) | TRPA1ATMKCNN4KIF11GABRA1 | |
| SCHEMBL8784814 | 0.73 | TSHR (0.43) | TRPA1ATMGABRA1GABRB2TSHR | |
| SCHEMBL6257499 | 0.73 | CA1 (0.46) | TRPA1MAPK1TSHRALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991006589-A1 | NEW ANTI-HIV COMPOUNDS BELONGING TO AURINTRICARBOXYLIC ACID | THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY, UNITED STATES DEPARTMENT OF COMMERCE (US) | 1991-05-16 | — | — | WO | disclosed |