Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 3/20 | 0.46 |
| ▸ | DRD3 | P35462 | 4/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 4/20 | 0.41 |
| ▸ | DRD2 | P14416 | 4/20 | 0.41 |
| ▸ | HTR1A | P08908 | 3/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.38 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7985498 | 0.71 | MEN1 (0.66) | MEN1MAPK10GFERKMT2A | |
| SCHEMBL9640183 | 0.69 | SIRT6 (0.47) | ACHEDRD3DRD2HTR1AHTR2A | |
| SCHEMBL9755216 | 0.68 | ELANE (0.45) | ACHEDRD3DRD2ELANEDRD4 | |
| Hydrochloric Acid SCHEMBL9639460 | 0.68 | SIRT6 (0.46) | ACHEDRD3DRD2HTR1AHTR2A | |
| SCHEMBL27814282 | 0.65 | HRH4 (0.56) | ACHEMEN1MAPK10KMT2A | |
| SCHEMBL20241784 | 0.64 | ACHE (0.70) | ACHEHTR1A | |
| SCHEMBL13472617 | 0.63 | DRD2 (0.61) | DRD3DRD2HTR1AHTR2ADRD4 | |
| SCHEMBL7985486 | 0.63 | MAPK10 (0.61) | MEN1MAPK10GFERKMT2A | |
| SCHEMBL27352770 | 0.63 | DRD3 (0.61) | DRD3ADRA1ADRD2HTR1AHTR2A | |
| SCHEMBL30416768 | 0.62 | SIRT6 (0.50) | DRD2HTR1AHTR2AELANESIRT6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991006542-A1 | PHARMACEUTICALLY ACTIVE AMINO-SUBSTITUTED HETEROARYL AMINES | THE UPJOHN COMPANY (US) | 1991-05-16 | — | — | WO | claimed |