Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | TP53 | P04637 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | CCR1 | P32246 | 2/20 | 0.47 |
| ▸ | CCR5 | P51681 | 2/20 | 0.47 |
| ▸ | CCR8 | P51685 | 2/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.47 |
| ▸ | GMNN | O75496 | 1/20 | 0.47 |
| ▸ | MMP2 | P08253 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | MMP9 | P14780 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9755469 | 0.82 | KDR (0.65) | HTTTDP1KDRNPC1RAB9A | |
| SCHEMBL9755462 | 0.81 | MDM2 (0.46) | SMN1; SMN2KDM4ELMNAHTTTP53 | |
| SCHEMBL28476553 | 0.76 | NPC1 (0.66) | SMN1; SMN2MAPTNFKB1MTORNPC1 | |
| SCHEMBL10788485 | 0.74 | CYP1A2 (0.61) | SMN1; SMN2KDM4ETP53MAPTCYP3A4 | |
| SCHEMBL28353091 | 0.73 | LMNA (0.67) | SMN1; SMN2KDM4ELMNAHTTTP53 | |
| SCHEMBL15673368 | 0.72 | CCR1 (0.64) | SMN1; SMN2KDM4ELMNAHTTTP53 | |
| SCHEMBL9755467 | 0.71 | L3MBTL1 (0.69) | SMN1; SMN2TP53MAPTTDP1KDR | |
| Phenanthroline SCHEMBL28130373 | 0.71 | CCR1 (0.94) | SMN1; SMN2KDM4ELMNAHTTTP53 | |
| SCHEMBL24733628 | 0.70 | RAB9A (0.63) | SMN1; SMN2KDM4ELMNAHTTTP53 | |
| SCHEMBL4891113 | 0.70 | TP53 (0.69) | SMN1; SMN2KDM4ELMNAHTTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991005785-A1 | 1,10-PHENANTHROLINE DERIVATIVES | VERENIGING VOOR CHRISTELIJK WETENSCHAPPELIJK ONDERWIJS (NL) | 1991-05-02 | — | — | WO | disclosed |