Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 4/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9330238 | 0.76 | HSD11B1 (0.36) | PKMHTTNLRP3HSD11B1ALDH1A1 | |
| SCHEMBL9330232 | 0.71 | ALDH1A1 (0.40) | PKMHTTALDH1A1LMNAKMT2A | |
| SCHEMBL8881202 | 0.67 | DAGLA (0.39) | HTTHSD11B1ALDH1A1LMNAKMT2A | |
| SCHEMBL9755577 | 0.67 | ALDH1A1 (0.36) | HTTALDH1A1KMT2A | |
| SCHEMBL9199985 | 0.64 | HSD11B1 (0.43) | PKMHTTNLRP3HSD11B1ALDH1A1 | |
| SCHEMBL96014 | 0.64 | NPSR1 (0.40) | HTTALDH1A1LMNAKMT2A | |
| SCHEMBL8881199 | 0.62 | DAGLA (0.39) | HTTHSD11B1ALDH1A1LMNAKMT2A | |
| SCHEMBL7317875 | 0.61 | FAAH (0.36) | HTTALDH1A1LMNAKMT2A | |
| SCHEMBL25669632 | 0.61 | NPSR1 (0.39) | HTTALDH1A1LMNAKMT2A | |
| SCHEMBL96013 | 0.60 | FAAH (0.39) | HTTALDH1A1LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991019707-A2 | ANTIATHEROSCLEROTIC AND ANTITHROMBOTIC 1-BENZOPYRAN-4-ONES AND 2-AMINO-1,3-BENZOXAZINE-4-ONES | THE UPJOHN COMPANY (US) | 1991-12-26 | — | — | WO | disclosed |