SCHEMBL9756192

SCHEMBL9756192

C=CCC(=O)NN(C(=O)c1ccccc1OC)C(C)(C)C

nearest known ligand 0.62

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ABCB1 P08183 1/20 0.47
CTSD P07339 1/20 0.43
LMNA P02545 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9756344 0.85 ABCB1 (0.51) ABCB1
SCHEMBL9756387 0.84 ABCB1 (0.47) ABCB1
SCHEMBL9756008 0.82 MAPT (0.46) ABCB1CTSD
SCHEMBL9755916 0.82 MEN1 (0.53) ABCB1LMNA
SCHEMBL9755896 0.81 ALDH1A1 (0.48)
SCHEMBL9756199 0.81 CTSD (0.49) ABCB1CTSDLMNA
SCHEMBL9755913 0.80 ABCB1 (0.51) ABCB1CTSD
SCHEMBL9714501 0.80 ABCB1 (0.60) ABCB1CTSD
SCHEMBL9755897 0.80 LMNA (0.48) LMNA
SCHEMBL9756326 0.80 HDAC8 (0.49)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0234944-B1 INSECTICIDAL N'-SUBSTITUTED-N-ACYL-N'-ALKYLCARBONYLHYDRAZINES ROHM AND HAAS COMPANY (US) 1991-04-10 EP disclosed
EP-0232075-B1 INSECTICIDAL N'-SUBSTITUTED-N-ALKYLCARBONYL-N'-ACYL HYDRAZINES ROHM AND HAAS COMPANY (US) 1991-03-13 EP disclosed
EP-0232075-A1 Insecticidal N'-substituted-N-alkylcarbonyl-N'-acyl hydrazines ROHM AND HAAS COMPANY (US) 1987-08-12 EP disclosed