Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APAF1 | O14727 | 9/20 | 0.47 |
| ▸ | MAPT | P10636 | 9/20 | 0.47 |
| ▸ | SENP6 | Q9GZR1 | 9/20 | 0.47 |
| ▸ | SENP7 | Q9BQF6 | 8/20 | 0.47 |
| ▸ | GAA | P10253 | 8/20 | 0.47 |
| ▸ | SENP8 | Q96LD8 | 5/20 | 0.47 |
| ▸ | PPP1CA | P62136 | 3/20 | 0.47 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.46 |
| ▸ | GBA1 | P04062 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.45 |
| ▸ | CASP1 | P29466 | 1/20 | 0.45 |
| ▸ | CASP4 | P49662 | 1/20 | 0.45 |
| ▸ | CASP5 | P51878 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | NSD2 | O96028 | 3/20 | 0.44 |
| ▸ | THRB | P10828 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6298691 | 0.81 | SENP6 (0.51) | APAF1MAPTSENP6SENP7GAA | |
| SCHEMBL9215848 | 0.78 | HRH4 (0.56) | APAF1MAPTSENP6SENP7GAA | |
| SCHEMBL3476846 | 0.77 | CASP1 (0.50) | APAF1MAPTSENP6SENP7GAA | |
| SCHEMBL9217636 | 0.76 | NUDT1 (0.68) | APAF1MAPTSENP6SENP7GAA | |
| SCHEMBL2773991 | 0.75 | CXCR4 (0.50) | APAF1MAPTSENP6SENP7GAA | |
| SCHEMBL3475816 | 0.75 | HRH4 (0.46) | APAF1MAPTSENP6SENP7GAA | |
| SCHEMBL23275374 | 0.74 | ALDH1A1 (0.51) | APAF1MAPTGAAKDM4ESMN1; SMN2 | |
| SCHEMBL16094408 | 0.74 | ALDH1A1 (0.51) | APAF1MAPTGAAKDM4ESMN1; SMN2 | |
| SCHEMBL16094407 | 0.74 | ALDH1A1 (0.51) | APAF1MAPTGAAKDM4ESMN1; SMN2 | |
| SCHEMBL23299875 | 0.72 | RAF1 (0.49) | KMT2AHTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991011453-A2 | 5-OXYGENATED-2,4,6-TRIAMINOPYRIMIDINES | THE UPJOHN COMPANY (US) | 1991-08-08 | — | — | WO | disclosed |