Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | GBA1 | P04062 | 6/20 | 0.46 |
| ▸ | STS | P08842 | 1/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 1/20 | 0.45 |
| ▸ | DPP4 | P27487 | 1/20 | 0.43 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.42 |
| ▸ | CKS1B | P61024 | 1/20 | 0.41 |
| ▸ | SKP1 | P63208 | 1/20 | 0.41 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.41 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9756677 | 0.91 | KMT2A (0.47) | MEN1KMT2ASMN1; SMN2GBA1PIK3CA | |
| SCHEMBL9756638 | 0.90 | GBA1 (0.49) | MEN1KMT2AGBA1PIK3CAADORA2A | |
| SCHEMBL9756685 | 0.89 | SMN1; SMN2 (0.48) | MEN1KMT2ASMN1; SMN2GBA1ADORA2A | |
| SCHEMBL9668922 | 0.81 | GPR119 (0.43) | GBA1ADORA2AADORA1CKS1BSKP1 | |
| SCHEMBL9756679 | 0.81 | GBA1 (0.55) | HTTGBA1CKS1BSKP1SKP2 | |
| SCHEMBL9756669 | 0.81 | HSD17B10 (0.49) | MEN1KMT2AHSD17B10SMN1; SMN2NPSR1 | |
| SCHEMBL9756696 | 0.78 | GPR119 (0.45) | GBA1ADORA2AADORA1CKS1BSKP1 | |
| SCHEMBL15921897 | 0.76 | CKS1B (0.55) | MEN1KMT2ASMN1; SMN2PIK3CAADORA2A | |
| SCHEMBL10297496 | 0.76 | GPR119 (0.55) | MEN1KMT2ASMN1; SMN2PIK3CAADORA2A | |
| 4-Methylbenzoic Acid SCHEMBL9671138 | 0.76 | GBA1 (0.48) | MEN1KMT2ASMN1; SMN2GBA1ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991011453-A2 | 5-OXYGENATED-2,4,6-TRIAMINOPYRIMIDINES | THE UPJOHN COMPANY (US) | 1991-08-08 | — | — | WO | claimed |