Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.45 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.44 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.44 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | GALR2 | O43603 | 1/20 | 0.42 |
| ▸ | GALR1 | P47211 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | GBA1 | P04062 | 3/20 | 0.42 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9756677 | 0.90 | KMT2A (0.47) | SMN1; SMN2GPR119TLR9TLR7GBA1 | |
| SCHEMBL9756680 | 0.89 | MEN1 (0.55) | SMN1; SMN2MAPTGPR119TLR9TLR7 | |
| SCHEMBL9756638 | 0.89 | GBA1 (0.49) | GPR119TLR9TLR7GBA1ADORA2A | |
| SCHEMBL9668922 | 0.81 | GPR119 (0.43) | MAPTLMNAALDH1A1GPR119TLR9 | |
| SCHEMBL9756679 | 0.80 | GBA1 (0.55) | TLR9TLR7GBA1 | |
| SCHEMBL9756696 | 0.77 | GPR119 (0.45) | MAPTLMNAALDH1A1GPR119TLR9 | |
| 4-Methylbenzoic Acid SCHEMBL9671138 | 0.75 | GBA1 (0.48) | SMN1; SMN2GPR119TLR9TLR7GBA1 | |
| SCHEMBL5233751 | 0.73 | L3MBTL1 (0.66) | SMN1; SMN2MAPTLMNAALDH1A1GPR119 | |
| SCHEMBL1458624 | 0.73 | L3MBTL1 (0.73) | SMN1; SMN2MAPTLMNAALDH1A1GPR119 | |
| SCHEMBL28494646 | 0.73 | MEN1 (0.67) | SMN1; SMN2MAPTLMNAALDH1A1GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991011453-A2 | 5-OXYGENATED-2,4,6-TRIAMINOPYRIMIDINES | THE UPJOHN COMPANY (US) | 1991-08-08 | — | — | WO | claimed |