Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | MME | P08473 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14452096 | 0.83 | LMNA (0.42) | HTTALDH1A1HPGDLMNAMAPT | |
| SCHEMBL11918239 | 0.82 | CYP2C19 (0.41) | ESR1ESR2ALDH1A1KDM4ELMNA | |
| SCHEMBL12380249 | 0.80 | NPSR1 (0.49) | HTTALDH1A1MMEHPGDKDM4E | |
| SCHEMBL9657022 | 0.80 | MC4R (0.46) | HTTALDH1A1HPGDKDM4ELMNA | |
| SCHEMBL16149256 | 0.77 | GABBR2 (0.46) | ESR1ESR2HTTHDAC3HDAC4 | |
| SCHEMBL4733307 | 0.77 | ESR1 (0.44) | ESR1ESR2HTTALDH1A1KDM4E | |
| SCHEMBL915370 | 0.76 | ALDH1A1 (0.51) | HTTALDH1A1HPGDKDM4ELMNA | |
| SCHEMBL684103 | 0.75 | ADRB2 (0.49) | ESR1ESR2HTTALDH1A1HPGD | |
| SCHEMBL10510650 | 0.75 | HTT (0.40) | HTTALDH1A1MMEHPGDKDM4E | |
| SCHEMBL2739002 | 0.74 | ESR1 (0.42) | ESR1ESR2HTTALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4992462-A | Inhibitor of HMG-CoA reductase | BAYER AKTIENGESELLSCHAFT (DE) | 1991-02-12 | — | — | US | disclosed |
| EP-0287890-A1 | Substituted pyrroles | BAYER AG (DE) | 1988-10-26 | — | — | EP | disclosed |