Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | NOS3 | P29474 | 1/20 | 0.43 |
| ▸ | NOS1 | P29475 | 1/20 | 0.43 |
| ▸ | NOS2 | P35228 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | MITF | O75030 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9756832 | 1.00 | PTGS2 (0.44) | PTGS2KDM4EALDH1A1SMN1; SMN2NOS3 | |
| SCHEMBL23015846 | 0.86 | NOS3 (0.46) | PTGS2KDM4EALDH1A1NOS3NOS1 | |
| SCHEMBL12501387 | 0.83 | NOS3 (0.40) | ALDH1A1NOS3NOS1NOS2PKM | |
| SCHEMBL2956488 | 0.78 | SMN1; SMN2 (0.42) | KDM4EALDH1A1SMN1; SMN2NOS3NOS1 | |
| SCHEMBL2956493 | 0.78 | SMN1; SMN2 (0.42) | KDM4EALDH1A1SMN1; SMN2NOS3NOS1 | |
| SCHEMBL22007014 | 0.78 | NOS2 (0.50) | KDM4ENOS3NOS1NOS2PKM | |
| SCHEMBL6642166 | 0.75 | NOS3 (0.52) | KDM4EALDH1A1SMN1; SMN2NOS3NOS1 | |
| SCHEMBL13964557 | 0.75 | ITGB2 (0.42) | KDM4EALDH1A1SMN1; SMN2P4HTMRAB9A | |
| SCHEMBL9000442 | 0.75 | NOS3 (0.47) | KDM4EALDH1A1SMN1; SMN2NOS3NOS1 | |
| SCHEMBL18989993 | 0.75 | NPSR1 (0.50) | KDM4EALDH1A1PKMP4HTMGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5039684-A | Absorption when administered orally | VALEAS S. P. A. (IT) | 1991-08-13 | — | — | US | disclosed |
| EP-0384450-A1 | Tetrazole amide derivatives of heterocyclic alkenyl acids and their use as antiallergic substances | VALEAS S.p.A. INDUSTRIA CHIMICA E FARMACEUTICA (IT) | 1990-08-29 | — | — | EP | disclosed |