Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 8/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.37 |
| ▸ | NPC1 | O15118 | 8/20 | 0.37 |
| ▸ | LMNA | P02545 | 7/20 | 0.37 |
| ▸ | MEN1 | O00255 | 7/20 | 0.37 |
| ▸ | HTT | P42858 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 10/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.36 |
| ▸ | XBP1 | P17861 | 1/20 | 0.36 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.34 |
| ▸ | RELA | Q04206 | 1/20 | 0.34 |
| ▸ | MITF | O75030 | 2/20 | 0.34 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9756846 | 0.85 | NPC1 (0.42) | MAPTKMT2ANPC1LMNAMEN1 | |
| SCHEMBL9756826 | 0.78 | RAB9A (0.60) | MAPTKMT2ANPC1LMNAMEN1 | |
| SCHEMBL9756894 | 0.75 | TAS1R3 (0.45) | EGFRMAPTKMT2ANPC1LMNA | |
| SCHEMBL9756976 | 0.74 | JUN (0.49) | EGFRMAPTKMT2ANPC1LMNA | |
| SCHEMBL9756853 | 0.72 | KMT2A (0.46) | MAPTKMT2ANPC1LMNAMEN1 | |
| SCHEMBL19003250 | 0.70 | MAPT (0.51) | EGFRMAPTKMT2ANPC1LMNA | |
| SCHEMBL9756888 | 0.70 | NAMPT (0.55) | MAPTNPC1RAB9AKDM4ENFKB1 | |
| SCHEMBL9756998 | 0.70 | KMT2A (0.40) | KMT2ANPC1LMNAMEN1HTT | |
| SCHEMBL9756980 | 0.70 | NPC1 (0.58) | MAPTKMT2ANPC1LMNAMEN1 | |
| SCHEMBL12892199 | 0.69 | PYGL (0.53) | MAPTKMT2ANPC1LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0384450-A1 | Tetrazole amide derivatives of heterocyclic alkenyl acids and their use as antiallergic substances | VALEAS S.p.A. INDUSTRIA CHIMICA E FARMACEUTICA (IT) | 1990-08-29 | — | — | EP | claimed |
| US-5039684-A | Absorption when administered orally | VALEAS S. P. A. (IT) | 1991-08-13 | — | — | US | disclosed |
| EP-0384450-A1 | Tetrazole amide derivatives of heterocyclic alkenyl acids and their use as antiallergic substances | VALEAS S.p.A. INDUSTRIA CHIMICA E FARMACEUTICA (IT) | 1990-08-29 | — | — | EP | disclosed |