Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 12/20 | 0.60 |
| ▸ | NPC1 | O15118 | 10/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 10/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.60 |
| ▸ | MAPT | P10636 | 5/20 | 0.58 |
| ▸ | LMNA | P02545 | 4/20 | 0.58 |
| ▸ | MEN1 | O00255 | 4/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | TP53 | P04637 | 2/20 | 0.58 |
| ▸ | HTT | P42858 | 2/20 | 0.58 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.58 |
| ▸ | GLA | P06280 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | GAPDH | P04406 | 1/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.51 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.51 |
| ▸ | RELA | Q04206 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9756846 | 0.78 | NPC1 (0.42) | RAB9ANPC1SMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL9756834 | 0.78 | EGFR (0.39) | RAB9ANPC1SMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL9756976 | 0.78 | JUN (0.49) | RAB9ANPC1SMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL9756894 | 0.76 | TAS1R3 (0.45) | RAB9ANPC1SMN1; SMN2KDM4EMAPT | |
| SCHEMBL9756853 | 0.76 | KMT2A (0.46) | RAB9ANPC1SMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL27911751 | 0.74 | NPC1 (0.63) | RAB9ANPC1SMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL9756888 | 0.74 | NAMPT (0.55) | RAB9ANPC1KDM4EMAPTNFKB1 | |
| SCHEMBL9756980 | 0.74 | NPC1 (0.58) | RAB9ANPC1SMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL9138103 | 0.73 | ALDH1A1 (0.56) | RAB9ANPC1SMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL18985299 | 0.73 | RAB9A (0.74) | RAB9ANPC1SMN1; SMN2ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5039684-A | Absorption when administered orally | VALEAS S. P. A. (IT) | 1991-08-13 | — | — | US | claimed |
| EP-0384450-A1 | Tetrazole amide derivatives of heterocyclic alkenyl acids and their use as antiallergic substances | VALEAS S.p.A. INDUSTRIA CHIMICA E FARMACEUTICA (IT) | 1990-08-29 | — | — | EP | claimed |