Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANXA2 | P07355 | 1/20 | 0.53 |
| ▸ | S100A10 | P60903 | 1/20 | 0.53 |
| ▸ | HSD11B1 | P28845 | 4/20 | 0.49 |
| ▸ | HTR6 | P50406 | 3/20 | 0.40 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 5/20 | 0.38 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.37 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.37 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.37 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | C1S | P09871 | 1/20 | 0.36 |
| ▸ | AKT1 | P31749 | 1/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11067612 | 0.81 | HSD11B1 (0.53) | HSD11B1HTR6AKR1B1NFE2L2CNR2 | |
| SCHEMBL9756875 | 0.78 | HSD11B1 (0.50) | HSD11B1HTR6AKR1B1NFE2L2ABCC9 | |
| SCHEMBL516500 | 0.78 | HSD11B1 (0.67) | HSD11B1HTR6AKR1B1ABCC9ABCC8 | |
| SCHEMBL9625077 | 0.77 | ANXA2 (0.71) | ANXA2S100A10HTR6 | |
| SCHEMBL9475449 | 0.76 | HSD11B1 (0.75) | HSD11B1HTR6AKR1B1ABCC9ABCC8 | |
| SCHEMBL27733744 | 0.74 | HSD11B1 (0.62) | HSD11B1HTR6AKR1B1ABCC9ABCC8 | |
| SCHEMBL248010 | 0.73 | HSD11B1 (0.59) | HSD11B1AKR1B1NFE2L2 | |
| SCHEMBL30697126 | 0.73 | HSD11B1 (0.59) | HSD11B1AKR1B1NFE2L2 | |
| SCHEMBL2123876 | 0.73 | HSD11B1 (0.59) | HSD11B1AKR1B1NFE2L2 | |
| SCHEMBL9403464 | 0.71 | HSD11B1 (0.68) | HSD11B1HTR6AKR1B1ABCC9ABCC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5037954-A | Method to recover liquified poly(arylene sulfide) with separation agent | PHILLIPS PETROLEUM COMPANY (US) | 1991-08-06 | — | — | US | disclosed |
| EP-0436120-A2 | Method to recover poly(arylene sulfide)s | PHILLIPS PETROLEUM COMPANY (US) | 1991-07-10 | — | — | EP | disclosed |