SCHEMBL9756875

SCHEMBL9756875

O=S(=O)(c1cccc(Br)c1)c1ccccc1Cl

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD11B1 P28845 5/20 0.50
FEN1 P39748 1/20 0.46
FLT1 P17948 1/20 0.43
FLT4 P35916 1/20 0.43
KDR P35968 1/20 0.43
C1S P09871 1/20 0.42
WDR5 P61964 1/20 0.41
HTR6 P50406 1/20 0.41
MMP2 P08253 1/20 0.40
AKR1B1 P15121 1/20 0.40
PGR P06401 1/20 0.39
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
NFE2L2 Q16236 1/20 0.39
MBTD1 Q05BQ5 1/20 0.38
L3MBTL3 Q96JM7 1/20 0.38
BRD4 O60885 1/20 0.38
ABCC9 O60706 1/20 0.38
ABCC8 Q09428 1/20 0.38
KCNJ11 Q14654 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11067612 0.82 HSD11B1 (0.53) HSD11B1FEN1HTR6AKR1B1PGR
SCHEMBL9475086 0.80 HSD11B1 (0.64) HSD11B1FEN1HTR6AKR1B1KMT2A
SCHEMBL516500 0.79 HSD11B1 (0.67) HSD11B1HTR6AKR1B1KMT2AABCC9
SCHEMBL31391247 0.79 LMNA (0.54) FEN1C1SWDR5HTR6MMP2
SCHEMBL3679487 0.79 LMNA (0.54) FEN1C1SWDR5HTR6MMP2
SCHEMBL31668877 0.79 LMNA (0.54) FEN1C1SWDR5HTR6MMP2
SCHEMBL9756860 0.78 ANXA2 (0.53) HSD11B1C1SHTR6AKR1B1NFE2L2
SCHEMBL29945255 0.77 HTR6 (0.61) HTR6MMP2PGRMEN1KMT2A
SCHEMBL3831593 0.77 HTR6 (0.61) HTR6MMP2PGRMEN1KMT2A
SCHEMBL16810 0.77 HSD11B1 (0.57) HSD11B1FEN1HTR6ABCC9ABCC8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5037954-A Method to recover liquified poly(arylene sulfide) with separation agent PHILLIPS PETROLEUM COMPANY (US) 1991-08-06 US disclosed
EP-0436120-A2 Method to recover poly(arylene sulfide)s PHILLIPS PETROLEUM COMPANY (US) 1991-07-10 EP disclosed